Chavoutier-Uzzan F, Bernuau J, Degott C, Rueff B, Benhamou J P
Service d'Hépatologie, INSERM U24, Clichy.
Gastroenterol Clin Biol. 1988 Aug-Sep;12(8-9):668-9.
The authors report the case of a 76 year-old woman affected by heatstroke complicated by massive liver cell necrosis and fulminant liver failure, with a favorable outcome. Liver cell necrosis was localized in centro- and medio-lobular areas and was not associated with hepatic vein congestion. These histological features suggest that the main causal factor of liver cell necrosis was relative liver cell hypoxia secondary to increased oxygen tissular requirements induced by hyperthermia.
作者报告了一例76岁女性中暑病例，该病例并发大量肝细胞坏死和暴发性肝衰竭，但预后良好。肝细胞坏死位于肝小叶中央和中间区域，与肝静脉淤血无关。这些组织学特征表明，肝细胞坏死的主要病因是高温引起的组织需氧量增加继发的相对性肝细胞缺氧。
