Institute of Information Systems, University of Applied Sciences Hof, Hof, Germany.
Institute of Medical Psychology and Medical Sociology, University of Rostock, Rostock, Germany.
Acta Neurol Scand. 2019 Apr;139(4):340-345. doi: 10.1111/ane.13065. Epub 2019 Jan 28.
The purpose of this work is the analysis of migraine attack reports collected online within the project Migraine Radar in respect to the distribution of the migraine attacks over the week on a single-participant level.
MATERIALS & METHODS: Recording data using a web app as well as smartphone apps made it possible to collect data of 44 639 migraine attacks of 1085 participants who reported seven or more attacks over a participation period of at least 90 days. This allows the investigation of attack distributions on a single-participant level. Considering the day of the week with the highest attack frequency for each participant-the mode of the individual distribution-allows identifying participants suffering from weekend migraines. Namely, a weekend pattern is assumed if the mode falls on a Saturday or Sunday.
For 15.9% of the participants, the attacks were not distributed equally (P < 0.05) over the days of the week. Instead, participants show different individual patterns for the distribution of their migraine attacks. Furthermore, the modes of the individual distributions are not distributed equally over the week. In fact, Saturday seems to be the predominant day for migraine attacks for a greater proportion of participants (195 of 1085).
Concerning the individual attack distributions, we found that participants show individual attack patterns and weekend migraine can be determined for a subgroup of participants, while other participants show accumulations of their attacks on other days of the week.
本研究旨在分析偏头痛发作报告项目 Migraine Radar 中在线收集的偏头痛发作数据,以个体水平上每周偏头痛发作的分布情况为分析对象。
通过网页应用程序和智能手机应用程序记录数据,共收集了 1085 名参与者的 44639 次偏头痛发作数据,这些参与者至少参与了 90 天,且报告了 7 次或以上的偏头痛发作。这使得我们能够在个体水平上研究发作分布情况。对于每个参与者,考虑到发作频率最高的一周中的某一天(即个体分布的众数),可以确定是否患有周末偏头痛。如果众数落在周六或周日,则假设存在周末模式。
15.9%的参与者在一周中的各天之间的发作分布不均(P<0.05)。相反,参与者的偏头痛发作分布呈现不同的个体模式。此外,个体分布的众数在一周内的分布也不均匀。实际上,对于更大比例的参与者(1085 名中的 195 名)来说,周六似乎是偏头痛发作的主要日子。
就个体发作分布而言,我们发现参与者表现出不同的个体发作模式,可确定亚组参与者存在周末偏头痛,而其他参与者的发作则集中在一周的其他日子。