Menon Sharika Venugopal, Paramu Raghukumar, Bhasi Saju, Nair Raghuram Kesavan
Division of Radiation Physics, Regional Cancer Centre, Thiruvananthapuram, Kerala, India.
J Med Phys. 2018 Oct-Dec;43(4):214-220. doi: 10.4103/jmp.JMP_25_18.
Several plan quality metrics are available for the evaluation of stereotactic radiosurgery/radiotherapy plans. This is a retrospective analysis of 60 clinical treatment plans of arteriovenous malformation (AVM) patients to study clinical usefulness of selected plan quality metrics.
The treatment coverage parameters Radiation Therapy Oncology Group (RTOG) Conformity Index (CI), RTOG Quality of Coverage (Q), RTOG Homogeneity Index (HI), Lomax Conformity Index (CI), Paddick's Conformity Index (CI), and dose gradient parameters Paddick's Gradient Index (GI) and Equivalent Fall-off Distance (EFOD) were calculated for the cohort of patients. Before analyzing patient plans, the influence of calculation grid size on selected plan quality metrics was studied on spherical targets.
It was found that the plan quality metrics are independent of calculation grid size ≤2 mm. EFOD was found to increase linearly with increase in target volume, and a linear fit equation was obtained.
The analysis shows that RTOG indices and EFOD would suffice for routine clinical radiosurgical treatment plan evaluation if a dose distribution is available for visual inspection.
有多种计划质量指标可用于评估立体定向放射外科/放射治疗计划。本研究对60例动静脉畸形(AVM)患者的临床治疗计划进行回顾性分析,以研究所选计划质量指标的临床实用性。
计算该队列患者的治疗覆盖参数,即放射治疗肿瘤学组(RTOG)适形指数(CI)、RTOG覆盖质量(Q)、RTOG均匀性指数(HI)、洛马克斯适形指数(CI)、帕迪克适形指数(CI),以及剂量梯度参数帕迪克梯度指数(GI)和等效衰减距离(EFOD)。在分析患者计划之前,在球形靶区研究了计算网格大小对所选计划质量指标的影响。
发现当计算网格大小≤2 mm时,计划质量指标与之无关。发现等效衰减距离随靶区体积的增加呈线性增加,并得到了线性拟合方程。
分析表明,如果有剂量分布可供目视检查,RTOG指标和等效衰减距离足以用于常规临床放射外科治疗计划评估。