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[卢本巴希地区胎心监护中观察到的胎儿心率异常研究:关于在卢本巴希大学诊所和五十周年总医院跟踪的病例]

[Study of fetal heart rate abnormalities observed on cardiotocography in Lubumbashi: about a cases followed at the Lubumbashi University Clinic and the General Hospital of the Cinquantenaire].

作者信息

Mwansa Joseph Chola, Tambwe Albert Mwembo, Thaba Jules Ngwe, Ndoudule Arthur Munkana, Museba Baudouin Yumba, Thabu Thérèse Mowa, Muenze Prosper Kalenga

机构信息

Département de Gynécologie-Obstétrique de la Faculté de Médecine de l'Université de Lubumbashi, Republique Démocratique du Congo.

Service de Gynécologie-Obstétrique de l'Hôpital Général du Cinquantenaire Karavia, Lubumbashi, Republique Démocratique du Congo.

出版信息

Pan Afr Med J. 2018 Aug 17;30:278. doi: 10.11604/pamj.2018.30.278.13365. eCollection 2018.

DOI:10.11604/pamj.2018.30.278.13365
PMID:30637063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6317385/
Abstract

Cardiotocography (CTG) has recently come into use in Lubumbashi but no thorough study has yet been conducted to identify its impact on perinatal morbi-mortality. This study aims to determine the frequency of fetal heart rate abnormalities (FHR)in order to identify the associated factors and to propose a suitable management. We conducted a cross-sectional, descriptive study of 411 women in labour over a period of 19 months (March 2015-December 2016). In patients with pathologic FHR abnormalities, sensitivity and positive predictive value of cardiotocography in the screening test for acute fetal distress were 82.95% and 45.35% respectively. FHR abnormalities were found in two women in labour out of five. Decelerations were the most frequent FHR abnormalities observed (50.8%) with a remarkable predominance of late decelerations (22.1% of all abnormalities). The factors associated with pathological FHR abnormalities were prolonged labor (OR = 14.64, CI = 3.91-54.81), chorioamnionitis (OR = 14.56, CI = 3.83-55.34), chronic maternal anemia (OR = 4.99, CI = 1.48-16.85), primiparity (OR = 2.69, CI = 1.49-4.85), prematurity (OR = 2.90, CI = 1.51-5.54) and prolonged pregnancy (OR = 3.22, CI = 1.38-7.52). Intrauterine growth retardation and arterial hypertension were mainly associated with flat lines and late decelerations (OR = 7.79, CI = 2.50-24.30 and OR=2.74, CI = 1.31-5.72). CTG is a screening tool for the identification of acute fetal distress but with high false-positive rate (55%); it should be associated with other second-line screening tests for acute fetal distress in order to reduce this rate. Factors associated with pathologic FHR abnormalities often cause acute fetal distress thus requiring a rigorous analysis of CTG traces.

摘要

胎心监护(CTG)最近在卢本巴希开始应用,但尚未进行全面研究以确定其对围产期发病率和死亡率的影响。本研究旨在确定胎儿心率异常(FHR)的频率,以识别相关因素并提出合适的管理措施。我们对19个月(2015年3月至2016年12月)期间411名分娩妇女进行了一项横断面描述性研究。在病理性FHR异常患者中,胎心监护在急性胎儿窘迫筛查试验中的敏感性和阳性预测值分别为82.95%和45.35%。每五名分娩妇女中有两名出现FHR异常。减速是观察到的最常见的FHR异常(50.8%),其中晚期减速显著占优势(占所有异常的22.1%)。与病理性FHR异常相关的因素有产程延长(OR = 14.64,CI = 3.91 - 54.81)、绒毛膜羊膜炎(OR = 14.56,CI = 3.83 - 55.34)、慢性母体贫血(OR = 4.99,CI = 1.48 - 16.85)、初产(OR = 2.69,CI = 1.49 - 4.85)、早产(OR = 2.90,CI = 1.51 - 5.54)和过期妊娠(OR = 3.22,CI = 1.38 - 7.52)。胎儿宫内生长受限和动脉高血压主要与基线平直和晚期减速相关(OR = 7.79,CI = 2.50 - 24.30和OR = 2.74,CI = 1.31 - 5.72)。胎心监护是识别急性胎儿窘迫的一种筛查工具,但假阳性率较高(55%);应将其与其他急性胎儿窘迫二线筛查试验联合使用以降低该比率。与病理性FHR异常相关的因素常导致急性胎儿窘迫,因此需要对胎心监护图形进行严格分析。

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本文引用的文献

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Clinical suspicion, management and outcome of intrapartum foetal distress in a public hospital with limited advanced foetal surveillance.一家先进胎儿监测手段有限的公立医院中,产时胎儿窘迫的临床怀疑、处理及结局
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Decreased baseline variability on fetal heart rate pattern in a fetus with heterotaxy syndrome.内脏异位综合征胎儿的胎心率图形基线变异减少。
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Continuous cardiotocography during labour: Analysis, classification and management.分娩期间的连续胎心监护:分析、分类与管理。
Best Pract Res Clin Obstet Gynaecol. 2016 Jan;30:33-47. doi: 10.1016/j.bpobgyn.2015.03.022. Epub 2015 Jun 25.
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Effect of Growth Restriction on Fetal Heart Rate Patterns in the Second Stage of Labor.生长受限对第二产程胎儿心率模式的影响。
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Cardiotocography patterns and risk of intrapartum fetal acidemia.胎心监护图形与产时胎儿酸血症风险
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Fetal heart rate pattern interpretation in the second stage of labor using the five-tier classification: impact of the degree and duration on severe fetal acidosis.使用五级分类法解读第二产程胎儿心率模式:程度和持续时间对严重胎儿酸中毒的影响
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