从支气管肺泡灌洗液体样本中分离出的耐唑类和对唑类敏感的土曲霉临床菌株的基因组序列草图
Draft Genome Sequences of Azole-Resistant and Azole-Susceptible Aspergillus turcosus Clinical Isolates Recovered from Bronchoalveolar Lavage Fluid Samples.
作者信息
Parent-Michaud Maxime, Dufresne Philippe J, Fournier Éric, Martineau Christine, Moreira Sandrine, Perkins Vincent, de Repentigny Louis, Dufresne Simon F
机构信息
Department of Microbiology, Infectious Diseases and Immunology, Université de Montréal, Montréal, Québec, Canada.
Laboratoire de santé publique du Québec, Institut national de santé publique du Québec, Sainte-Anne-de-Bellevue, Québec, Canada.
出版信息
Microbiol Resour Announc. 2019 Jan 3;8(1). doi: 10.1128/MRA.01446-18. eCollection 2019 Jan.
Abstract
We present the draft genome sequences of two clinical strains of Aspergillus turcosus, one azole-susceptible (strain HMR-AF-23/LSPQ-01275) and the other azole-resistant (strain HMR-AF-1038/LSPQ-01280), isolated from bronchoalveolar lavage fluid of two adult patients. These two strains are the first reported clinical isolates of A. turcosus.
摘要
我们展示了两株土耳其曲霉临床菌株的基因组序列草图，一株对唑类敏感（菌株HMR-AF-23/LSPQ-01275），另一株对唑类耐药（菌株HMR-AF-1038/LSPQ-01280），它们分别从两名成年患者的支气管肺泡灌洗 fluid中分离得到。这两株菌株是首次报道的土耳其曲霉临床分离株。 （注：原文中“bronchoalveolar lavage fluid”的“fluid”未翻译完整，可能是“液体”之类的意思，这里按字面翻译了）
相似文献
1
Draft Genome Sequences of Azole-Resistant and Azole-Susceptible Aspergillus turcosus Clinical Isolates Recovered from Bronchoalveolar Lavage Fluid Samples.从支气管肺泡灌洗液体样本中分离出的耐唑类和对唑类敏感的土曲霉临床菌株的基因组序列草图
Microbiol Resour Announc. 2019 Jan 3;8(1). doi: 10.1128/MRA.01446-18. eCollection 2019 Jan.
2
Draft Genome Sequence of Azole-Resistant Aspergillus thermomutatus (Neosartorya pseudofischeri) Strain HMR-AF-39, Isolated from a Human Nasal Septum Abscess Aspirate.从人鼻中隔脓肿抽吸物中分离出的耐唑类热突变曲霉（拟费氏新萨托菌）菌株HMR-AF-39的基因组序列草图
Microbiol Resour Announc. 2019 Jan 3;8(1). doi: 10.1128/MRA.01444-18. eCollection 2019 Jan.
3
Validation of a new Aspergillus real-time PCR assay for direct detection of Aspergillus and azole resistance of Aspergillus fumigatus on bronchoalveolar lavage fluid.一种用于直接检测支气管肺泡灌洗液中曲霉菌及烟曲霉唑类耐药性的新型曲霉菌实时聚合酶链反应检测方法的验证
J Clin Microbiol. 2015 Mar;53(3):868-74. doi: 10.1128/JCM.03216-14. Epub 2015 Jan 7.
4
The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatus.cdr1B 外排转运蛋白与烟曲霉中非 Cyp51a 介导的伊曲康唑耐药性相关。
J Antimicrob Chemother. 2013 Jul;68(7):1486-96. doi: 10.1093/jac/dkt075. Epub 2013 Apr 10.
5
[Phenotypic and Genotypic Evaluation of Azole Resistance in Aspergillus fumigatus Isolates from Clinical and Environmental Specimens].[来自临床和环境样本的烟曲霉分离株中唑类耐药性的表型和基因型评估]
Mikrobiyol Bul. 2020 Apr;54(2):291-305. doi: 10.5578/mb.69024.
6
7
Genomic perspective of triazole resistance in clinical and environmental Aspergillus fumigatus isolates without cyp51A mutations.临床和环境烟曲霉分离株中唑类耐药的基因组视角，这些分离株中没有 cyp51A 突变。
Fungal Genet Biol. 2019 Nov;132:103265. doi: 10.1016/j.fgb.2019.103265. Epub 2019 Aug 26.
8
Azole resistance in Aspergillus species in Southern Taiwan: An epidemiological surveillance study.台湾南部曲霉菌属中唑类耐药性：一项流行病学监测研究。
Mycoses. 2019 Dec;62(12):1174-1181. doi: 10.1111/myc.13008. Epub 2019 Oct 6.
9
Culture-Based Methods and Molecular Tools for Azole-Resistant Aspergillus fumigatus Detection in a Belgian University Hospital.比利时某大学医院中用于检测耐唑类烟曲霉的基于培养的方法和分子工具
J Clin Microbiol. 2017 Aug;55(8):2391-2399. doi: 10.1128/JCM.00520-17. Epub 2017 May 17.
10
Non-cyp51A Azole-Resistant Aspergillus fumigatus Isolates with Mutation in HMG-CoA Reductase.非细胞色素 P450 51A 唑类耐药烟曲霉分离株与 HMG-CoA 还原酶突变相关。
Emerg Infect Dis. 2018 Oct;24(10):1889-1897. doi: 10.3201/eid2410.180730.
引用本文的文献
1
Extremely acidophilic filamentous fungi are more prevalent in diverse ecosystems than previously documented.极端嗜酸丝状真菌在多样生态系统中的分布比之前记录的更为普遍。
Sci Rep. 2025 Aug 19;15(1):30445. doi: 10.1038/s41598-025-06321-1.
2
Examining Signatures of Natural Selection in Antifungal Resistance Genes Across Fungi.探究真菌中抗真菌抗性基因的自然选择特征
Front Fungal Biol. 2021 Sep 10;2:723051. doi: 10.3389/ffunb.2021.723051. eCollection 2021.
3
Extensive non-coding sequence divergence between the major human pathogen and its relatives.主要人类病原体与其亲缘物种之间广泛的非编码序列差异。
Front Fungal Biol. 2022;3. doi: 10.3389/ffunb.2022.802494. Epub 2022 Jul 7.
4
Cerebrospinal Fluid from Healthy Pregnant Women Does Not Harbor a Detectable Microbial Community.健康孕妇的脑脊液中不存在可检测的微生物群落。
Microbiol Spectr. 2021 Dec 22;9(3):e0076921. doi: 10.1128/Spectrum.00769-21. Epub 2021 Dec 15.
5
Prevalence and mechanisms of azole resistance in clinical isolates of Aspergillus section Fumigati species in a Canadian tertiary care centre, 2000 to 2013.2000 年至 2013 年，在加拿大一家三级保健中心，烟曲霉属雾霉菌组临床分离株中唑类药物耐药的流行情况和机制。
J Antimicrob Chemother. 2020 Apr 1;75(4):849-858. doi: 10.1093/jac/dkz534.
本文引用的文献
1
BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs.BUSCO：利用单拷贝同源基因评估基因组组装和注释的完整性。
Bioinformatics. 2015 Oct 1;31(19):3210-2. doi: 10.1093/bioinformatics/btv351. Epub 2015 Jun 9.
2
Phylogeny, identification and nomenclature of the genus Aspergillus.曲霉属的系统发育、鉴定与命名
Stud Mycol. 2014 Jun;78:141-73. doi: 10.1016/j.simyco.2014.07.004.
3
Trimmomatic: a flexible trimmer for Illumina sequence data.Trimmomatic：一款适用于 Illumina 测序数据的灵活修剪工具。
Bioinformatics. 2014 Aug 1;30(15):2114-20. doi: 10.1093/bioinformatics/btu170. Epub 2014 Apr 1.
4
QUAST: quality assessment tool for genome assemblies.QUAST：基因组组装质量评估工具。
Bioinformatics. 2013 Apr 15;29(8):1072-5. doi: 10.1093/bioinformatics/btt086. Epub 2013 Feb 19.
5
Clinical epidemiology of 960 patients with invasive aspergillosis from the PATH Alliance registry.960 例侵袭性曲霉菌病患者的临床流行病学分析：PATH 联盟注册研究。
J Infect. 2012 Nov;65(5):453-64. doi: 10.1016/j.jinf.2012.08.003. Epub 2012 Aug 13.
6
Wild-type MIC distributions and epidemiological cutoff values for the triazoles and six Aspergillus spp. for the CLSI broth microdilution method (M38-A2 document).CLSI 肉汤微量稀释法（M38-A2 文件）中三唑类药物和六种曲霉菌属的野生型 MIC 分布和流行病学折点值。
J Clin Microbiol. 2010 Sep;48(9):3251-7. doi: 10.1128/JCM.00536-10. Epub 2010 Jun 30.
7
Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database.2001-2006 年造血干细胞移植受者侵袭性真菌感染的前瞻性监测：移植相关感染监测网络（TRANSNET）数据库概述。
Clin Infect Dis. 2010 Apr 15;50(8):1091-100. doi: 10.1086/651263.
8
Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET).器官移植受者中的侵袭性真菌感染：移植相关感染监测网络（TRANSNET）的结果。
Clin Infect Dis. 2010 Apr 15;50(8):1101-11. doi: 10.1086/651262.
9
Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network.用于移植相关感染监测网络的曲霉属种的分子鉴定。
J Clin Microbiol. 2009 Oct;47(10):3138-41. doi: 10.1128/JCM.01070-09. Epub 2009 Aug 12.
10
Epidemiology and outcome of invasive fungal infection in adult hematopoietic stem cell transplant recipients: analysis of Multicenter Prospective Antifungal Therapy (PATH) Alliance registry.成年造血干细胞移植受者侵袭性真菌感染的流行病学及转归：多中心前瞻性抗真菌治疗（PATH）联盟登记研究分析
Clin Infect Dis. 2009 Feb 1;48(3):265-73. doi: 10.1086/595846.
Zotero 插件