Department of Dentistry, Faculty of Medicine in Hradec Kralove, University Hospital in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
Department of Obstetrics and Gynecology, Faculty of Medicine in Hradec Kralove, University Hospital in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
J Clin Periodontol. 2019 Feb;46(2):189-196. doi: 10.1111/jcpe.13067. Epub 2019 Feb 3.
Periodontal disease is a possible contributing factor to preterm delivery. The aim of this study was to compare the periodontal status of women with preterm prelabour rupture of membranes (PPROM) and women with uncomplicated singleton pregnancies.
Seventy-eight women with PPROM at gestational ages between 24 + 0 and 36 + 6 weeks and 77 healthy women with uncomplicated pregnancies, matched for gestational age at sampling without preterm birth, were included in this study. All women underwent evaluation of periodontal and oral hygiene status.
Women with PPROM had higher gingival and plaque indexes in crude analysis (gingival index: median 0.80 versus 0.20; p < 0.0001; plaque index: median 0.80 versus 0.10; p < 0.0001), even after adjustment for smoking status (p < 0.0001 and p < 0.0001). Mean clinical attachment loss (CAL) and probing pocket depth (PPD) values were higher in women with PPROM in the crude analysis (CAL: median 2.3 mm versus 1.8 mm; p < 0.0001; PPD: median 2.3 mm versus 1.8; p < 0.0001), as well as after adjustment for smoking status (p < 0.0001 and p < 0.0001).
Pregnant women with PPROM residing in central Europe had worse periodontal status than women with uncomplicated pregnancies.
牙周病可能是早产的一个致病因素。本研究旨在比较胎膜早破伴早产（PPROM）和无并发症单胎妊娠孕妇的牙周状况。
本研究纳入了 78 名在妊娠 24+0 至 36+6 周期间发生 PPROM 的孕妇和 77 名健康的、无早产的、与采样时孕龄相匹配的单胎妊娠孕妇。所有孕妇均接受牙周和口腔卫生状况评估。
未经校正时，PPROM 组孕妇的牙龈和菌斑指数更高（牙龈指数：中位数 0.80 比 0.20；p<0.0001；菌斑指数：中位数 0.80 比 0.10；p<0.0001），即使校正了吸烟状态（p<0.0001 和 p<0.0001）。未经校正时，PPROM 组孕妇的平均临床附着丧失（CAL）和探诊深度（PPD）值更高（CAL：中位数 2.3mm 比 1.8mm；p<0.0001；PPD：中位数 2.3mm 比 1.8mm；p<0.0001），校正了吸烟状态后仍然如此（p<0.0001 和 p<0.0001）。
居住在中欧的 PPROM 孕妇的牙周状况比无并发症的妊娠孕妇差。
