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利用杀锥虫治疗和对牛喷洒敌敌畏来维持乌干达控制动物源性昏睡病的努力。

Sustaining Efforts of Controlling Zoonotic Sleeping Sickness in Uganda Using Trypanocidal Treatment and Spray of Cattle with Deltamethrin.

机构信息

1Uganda Trypanosomiasis Control Council (UTCC) Secretariat, Coordinating Office for Control of Trypanosomiasis in Uganda (COCTU), Wandegeya-Kampala, Uganda.

2School of Veterinary Medicine and Animal Resources (SVAR), College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

出版信息

Vector Borne Zoonotic Dis. 2019 Aug;19(8):613-618. doi: 10.1089/vbz.2018.2382. Epub 2019 Jan 14.

DOI:10.1089/vbz.2018.2382
PMID:30638437
Abstract

In 2005, the zoonotic acute sleeping sickness was spreading rapidly from the endemic areas of southeastern Uganda with potential for merger into areas affected by the chronic form of the disease in northwest Uganda. Movement of cattle reservoirs due to restocking was blamed for the rapid spread. To stop the spread of the zoonotic sleeping sickness, cattle in the disease endemic areas had to be treated with trypanocidal drugs and sprayed with deltamethrin to promote the live bait technology that helps suppress the tsetse vector. The initiative that started in five high-risk districts in 2006 with a mix of using several undergraduate veterinary students has now been integrated in the local government veterinary service delivery in 23 high-risk districts. By 2016, the annual spray of cattle with deltamethrin and treatment with diminazene aceturate had reached one million with 1,065,444 cattle sprayed in the reporting year July 1, 2016 to June 30, 2017. This is believed to have contributed significantly to the reduction in the number of sleeping sickness cases (from 473 recorded in 2005 to 14 in 2016, and only about 10 reported to the Coordinating Office for Control of Trypanosomiasis in Uganda [COCTU] in 2017). The initiative that started as the Stamp Out Sleeping Sickness Consortium with a public good approach, implemented in a public-private partnership with the faculty of Veterinary Medicine, Makerere University, has today been integrated in both private and public sectors to fast-track the elimination of sleeping sickness with active financial contribution from the affected communities in sustaining the delivery of live bait technology.

摘要

2005 年,从乌干达东南部的地方性流行地区迅速传播的动物源性急性昏睡病有可能与乌干达西北部的慢性形式疾病流行地区合并。由于重新放养,牛等牲畜的流动被归咎于该病的迅速传播。为了阻止动物源性昏睡病的传播,必须用杀锥虫药物治疗疾病流行地区的牛,并喷洒除虫菊酯,以推广有助于抑制采采蝇媒介的活诱饵技术。该倡议于 2006 年在五个高风险地区启动,结合使用了几名本科兽医学生,现在已纳入 23 个高风险地区的地方政府兽医服务提供中。到 2016 年,每年对牛喷洒除虫菊酯和用二硝乙酰替苯胺治疗的次数已达到 100 万次,在报告年度(2016 年 7 月 1 日至 2017 年 6 月 30 日)有 1065444 头牛接受了喷洒。这被认为是昏睡病病例数量减少的重要原因(从 2005 年记录的 473 例减少到 2016 年的 14 例,而 2017 年仅向乌干达锥虫病防治协调办公室报告了 10 例)。该倡议最初以公共利益为出发点,作为消灭昏睡病联合会开展,与马凯雷雷大学兽医学院合作,以公私伙伴关系实施,如今已纳入私营和公共部门,以快速消除昏睡病,受影响社区积极提供财政捐助,以维持活诱饵技术的提供。

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