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半月板同种异体移植后重返运动活动:在什么水平和什么代价?系统评价和荟萃分析。

Return to Sport Activity After Meniscal Allograft Transplantation: At What Level and at What Cost? A Systematic Review and Meta-analysis.

机构信息

Clinica Ortopedica e Traumatologica II, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

Division of Sports Medicine and Shoulder Surgery, Department of Orthopaedic Surgery, Naval Medical Center San Diego, San Diego, California.

出版信息

Sports Health. 2019 Mar/Apr;11(2):123-133. doi: 10.1177/1941738118819723. Epub 2019 Jan 14.

Abstract

CONTEXT

: Meniscal injuries are common among both sport- and non-sport-related injuries, with over 1.7 million meniscal surgeries performed worldwide every year. As meniscal surgeries become more common, so does meniscal allograft transplantation (MAT). However, little is known about the outcomes of MAT in active patients who desire to go back to preinjury activities.

OBJECTIVE

: The purpose of this systematic review and meta-analysis was to evaluate return to sport, clinical outcome, and complications after MAT in sport-active patients.

DATA SOURCES

: A systematic search of MEDLINE, EMBASE, and CINAHL electronic databases was performed on February 25, 2018.

STUDY SELECTION

: Studies of level 1 through 4 evidence looking at MAT in physically active patients with reported return to activity outcomes and at least 2-year follow-up were included.

STUDY DESIGN

: Systematic review and meta-analysis.

LEVEL OF EVIDENCE

: Level 4.

DATA EXTRACTION

: Details of sport-related outcomes and reoperations were extracted and pooled in a meta-analysis.

RESULTS

: Nine studies were included in this systematic review. A majority (77%) of athletes and physically active patients were able to return to sport after MAT; two-thirds were able to perform at preinjury levels. Graft-related reoperations were reported in 13% of patients, while the joint replacement rate with partial or total knee prosthesis was 1.2%.

CONCLUSION

: Physical activity after MAT appears possible, especially for low-impact sports. However, because of the limited number of studies, their low quality, and the short-term follow-up, the participation recommendation for high-impact and strenuous activities should be considered with caution until high-quality evidence of long-term safety becomes available.

摘要

背景

半月板损伤在运动和非运动相关损伤中都很常见,全世界每年有超过 170 万例半月板手术。随着半月板手术的日益普及,半月板同种异体移植(MAT)也越来越常见。然而,对于渴望恢复受伤前活动水平的活跃患者,MAT 的结果知之甚少。

目的

本系统评价和荟萃分析的目的是评估运动活跃患者接受 MAT 后的重返运动、临床结果和并发症。

资料来源

于 2018 年 2 月 25 日对 MEDLINE、EMBASE 和 CINAHL 电子数据库进行了系统检索。

研究选择

纳入了 1 至 4 级证据水平的研究,这些研究观察了活跃患者的 MAT,报告了恢复活动的结果,且随访时间至少 2 年。

研究设计

系统评价和荟萃分析。

证据水平

4 级。

资料提取

提取并汇总了与运动相关的结果和再次手术的详细信息进行荟萃分析。

结果

本系统评价共纳入 9 项研究。大多数(77%)运动员和活跃患者在接受 MAT 后能够重返运动;三分之二的患者能够恢复到受伤前的运动水平。13%的患者报告了与移植物相关的再次手术,而部分或全膝关节置换的关节置换率为 1.2%。

结论

MAT 后进行身体活动似乎是可能的,尤其是对于低冲击运动。然而,由于研究数量有限、质量较低以及随访时间较短,在获得长期安全性的高质量证据之前,对于高冲击和剧烈活动的参与建议应谨慎考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38f8/6391552/cb59f18e5645/10.1177_1941738118819723-fig1.jpg

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