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与多发性硬化症干扰素-β治疗相关的肺动脉高压。病例报告及文献复习。

Pulmonary arterial hypertension associated with interferon-beta treatment for multiple sclerosis. Case report and literature review.

机构信息

Onassis Cardiac Surgery Center, Noninvasive Department of Cardiology, Athens, Greece.

Onassis Cardiac Surgery Center, Interventional Department of Cardiology, Athens, Greece.

出版信息

Mult Scler Relat Disord. 2019 Feb;28:273-275. doi: 10.1016/j.msard.2019.01.018. Epub 2019 Jan 6.

Abstract

Drug-Induced Pulmonary Arterial Hypertension (PAH) represents a well-known entity, predominantly related to anorexigens. Interferon-β (IFN) is considered to be a drug with a possible risk of inducing PAH. We report a patient with Multiple Sclerosis treated with IFN-β who diagnosed with PAH and her course of disease under specific PAH drug therapy. A review of the literature in IFN-β-induced PAH is provided.

摘要

药物性肺动脉高压(PAH)是一种众所周知的疾病,主要与食欲抑制剂有关。干扰素-β(IFN)被认为是一种可能导致 PAH 的药物。我们报告了一例接受 IFN-β 治疗的多发性硬化症患者,该患者被诊断为 PAH,并在特定的 PAH 药物治疗下的疾病过程。还对 IFN-β 引起的 PAH 的文献进行了回顾。

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