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[广州某社区老年居民肥胖/超重与中医体质/心血管危险因素的相关性分析]

[Correlation Analyses between Obesity/Overweight and Constitutions of Chinese Medicine/Cardio- vascular Risk Factors in Elderly Residents of a Community in Guangzhou].

作者信息

Huang Qin, Zhao Xiao-Shan, Sun Shi-Ning, He Li-Qing, Yang Jing, Chen Jie-Yu, Luo Ren

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2016 Oct;36(10):1208-1212.

PMID:30641008
Abstract

Objective To analyze the correlation between obesity/overweight and constitutions of Chinese medicine (CM)/cardiovascular risk factors in elderly residents of Tianhe District Wushan Com- munity, Guangzhou City. Methods Recruited were 1 054 elderly residents (over 60 years), who had free health examinations in Tianhe District Wushan Community of Guangzhou City from October 2014 to September 2015. They were assigned to the obesity group (107 cases) , the overweight group (431 ca- ses) , and the normal weight group (516 cases) according to body mass index (BMI) by randomized sampling. Constitution types of CM were assessed using Classification and Judgment of Constitution Types of CM. Health files were filled in. General indices such as waist circumference, blood pressure, etc., and blood biochemical indicators such as fasting blood glucose, blood lipids, uric acid, blood creati- nine, etc. were detected. The correlation between constitution types of CM and obesity/overweight was analyzed using multivariate Logistic regression analysis. Results Among the 1 054 elderly residents, 75. 62% (797/1 054) of those were of biased constitution and 24. 38% (257/1 054) were of normal consti- tution. Phlegm dampness (247 cases, 23. 43%), yin deficiency (150 cases, 14. 23%), and qi deficiency (136 cases, 12. 90%) constitution were top 3 commonly seen biased constitution types. Multiple Logistic regression analysis showed that the risk of obese/overweight patients of phlegm dampness constitution was 61. 641 times (Cl: 24. 491 -155. 144) and 9. 393 times (Cl: 5. 910 -14. 929) that of subjects of nor- mal constitution respectively (P <0. 01) ; the risk of obese/overweight patients of dampness heat consti- tution was 21. 478 times (Cl: 6. 978 -66. 102) and 4. 505 times ( Cl: 2. 308 -8. 793) that of subjects of normal constitution respectively (P <0. 01) ; the risk of obese/overweight patients of qi deficiency consti- tution was 3.408 times ( Cl:1. 161 -10. 004) and 1. 655 times (Cl: 1. 062 -2. 580) that of subjects of nor- mal constitution respectively (P <0. 05). Compared with normal body weight senile, the incidences of ab- dominal obesity, hypertension, diabetes were obviously higher in obese/overweight senile (P <0. 01 , P < 0. 05). Their values of fasting blood glucose, triglyceride, high-density lipoprotein, and uric acid were ob- viously higher than those in normal body weight senile (P <0. 01). Conclusions Community obese/over- weighed elderly residents have the tendency of phlegm dampness, dampness heat, and qi deficiency constitutions. Compared with the normal body weight senile, they have higher risk of cardiovascular risk factors, and increased risks of suffering from hypertension, diabetes, and dyslipidemia.

摘要

目的 分析广州市天河区五山社区老年居民肥胖/超重与中医体质及心血管危险因素之间的相关性。方法 选取2014年10月至2015年9月在广州市天河区五山社区进行免费健康体检的1 054名60岁以上老年居民,采用随机抽样法,根据体质指数(BMI)将其分为肥胖组(107例)、超重组(431例)和正常体重组(516例)。采用《中医体质分类与判定》评估中医体质类型,填写健康档案,检测腰围、血压等一般指标及空腹血糖、血脂、尿酸、血肌酐等血液生化指标。采用多因素Logistic回归分析中医体质类型与肥胖/超重的相关性。结果 1 054名老年居民中,偏颇体质者占75.62%(797/1 054),平和体质者占24.38%(257/1 054)。痰湿质(247例,23.43%)、阴虚质(150例,14.23%)、气虚质(136例,12.90%)为前3位常见的偏颇体质类型。多因素Logistic回归分析显示,肥胖/超重痰湿质患者发生肥胖/超重的风险分别是平和质者的61.641倍(95%CI:24.491 - 155.144)和9.393倍(95%CI:5.910 - 14.929)(P < 0.01);肥胖/超重湿热质患者发生肥胖/超重的风险分别是平和质者的21.478倍(95%CI:6.978 - 66.102)和4.505倍(95%CI:2.308 - 8.793)(P < 0.01);肥胖/超重气虚质患者发生肥胖/超重的风险分别是平和质者的3.408倍(95%CI:1.161 - 10.004)和1.655倍(95%CI:1.062 - 2.580)(P < 0.05)。与正常体重老年人相比,肥胖/超重老年人腹型肥胖、高血压、糖尿病的发生率明显更高(P < 0.01,P < 0.05)。其空腹血糖、甘油三酯、高密度脂蛋白、尿酸值明显高于正常体重老年人(P < 0.01)。结论 社区肥胖/超重老年居民具有痰湿质、湿热质、气虚质倾向。与正常体重老年人相比,其心血管危险因素风险更高,患高血压、糖尿病、血脂异常的风险增加。

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