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超声引导下颈椎椎间孔硬膜外类固醇注射治疗神经根型颈椎病的有效性:一项前瞻性初步研究。

The effectiveness of ultrasound-guided cervical transforaminal epidural steroid injections in cervical radiculopathy: a prospective pilot study.

作者信息

Zhang Xin, Shi Haifeng, Zhou Jin, Xu Yongming, Pu Shaofeng, Lv Yingying, Wu Junzhen, Cheng Yueping, Du Dongping

机构信息

Department of Anesthesiology, Pain Management Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China,

Center for Translational Pain Medicine, Department of Anesthesiology, Duke University School of Medicine, Durham, NC, USA,

出版信息

J Pain Res. 2018 Dec 31;12:171-177. doi: 10.2147/JPR.S181915. eCollection 2019.

Abstract

BACKGROUND

Cervical transforaminal epidural steroid injection (CTFESI) is used to provide pain relief and restore function in patients with cervical radiculopathy. Traditionally, it is performed under the guidance of fluoroscopy or computed tomography. Here, we introduce a novel technique - ultrasound-guided CTFESI - with which operators can easily distinguish the close soft tissue (nerve, vessels) around the cervical foramina to avoid intravascular injection during the procedure.

OBJECTIVE

To present the immediate and long-term effectiveness of ultrasound-guided CTFESI in patients with cervical radiculopathy in an academic pain-management center with prospective clinic experiments.

METHODS

Fifteen patients with cervical radiculopathy who were resistant to conservative therapies and ultrasound-guided selective cervical spinal nerve-root injections, were treated with ultrasound-guided CTFESI. During the injection procedures, the needle tips were reconfirmed by real-time fluoroscopy. Pain numeric rating-scale and neck-disability-index scores were assessed from onset to six months after the procedures.

RESULTS

During the procedures, based on real-time fluoroscopic confirmation, the injection solution outlined the spinal nerve root and spread into the epidural space in most cases (14 of 15). All patients reported pain relief within 10 minutes after the injection. The majority of patients (eleven of 15) experienced pain relief and neck-disability index-score improvement throughout the 6-month study period. No patient experienced any complication.

CONCLUSION

We suggest that ultrasound-guided CTFESI is an effective, safe, and simple procedure free of radiation or magnetization and provides sustained pain relief in patients with cervical radiculopathy who have failed previous conservation therapies.

摘要

背景

颈椎经椎间孔硬膜外类固醇注射(CTFESI)用于缓解颈椎神经根病患者的疼痛并恢复其功能。传统上,该操作在荧光透视或计算机断层扫描引导下进行。在此,我们介绍一种新技术——超声引导下的CTFESI,通过该技术,操作人员可以轻松区分颈椎椎间孔周围紧密的软组织(神经、血管),以避免在操作过程中血管内注射。

目的

通过前瞻性临床实验,在一个学术性疼痛管理中心展示超声引导下CTFESI治疗颈椎神经根病患者的即时和长期疗效。

方法

15例对保守治疗和超声引导下选择性颈椎脊神经根注射耐药的颈椎神经根病患者,接受了超声引导下的CTFESI治疗。在注射过程中,通过实时荧光透视再次确认针尖位置。在治疗开始至治疗后6个月期间评估疼痛数字评定量表和颈部功能障碍指数评分。

结果

在操作过程中,根据实时荧光透视确认,在大多数病例(15例中的14例)中,注射溶液勾勒出脊神经根并扩散到硬膜外间隙。所有患者在注射后10分钟内均报告疼痛缓解。在整个6个月的研究期间,大多数患者(15例中的11例)疼痛缓解且颈部功能障碍指数评分有所改善。没有患者出现任何并发症。

结论

我们认为,超声引导下的CTFESI是一种有效、安全且简单的无辐射或磁化的操作,可为先前保守治疗失败的颈椎神经根病患者提供持续的疼痛缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c47/6318715/4b290c658fd4/jpr-12-171Fig1.jpg

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