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颈椎经椎间孔硬膜外类固醇注射术后疼痛与功能改善情况的观察性研究

Benefit of pain and function after cervical transforaminal epidural steroid injections, an observational study.

作者信息

Goyal Kush K, Kristoff Tyler J, Sinopoli Jacob T, Abbott Matthew, Thompson Nicolas R, Koech Hilary, Rabah Nicholas

机构信息

Center for Spine Health, Neurological Institute, Cleveland Clinic, Cleveland, USA.

J. Willis Hurst Internal Medicine Residency Program, Emory University School of Medicine, Atlanta, USA.

出版信息

Interv Pain Med. 2023 Nov 23;2(4):100299. doi: 10.1016/j.inpm.2023.100299. eCollection 2023 Dec.

Abstract

OBJECTIVE

To evaluate the improvement of pain and function after cervical transforaminal epidural steroid injections (CTFESI) for radicular pain.

DESIGN

This is a retrospective observational study of patients receiving fluoroscopically-guided cervical transforaminal epidural steroid injections under a single provider at a tertiary referral center from December 2013 to December 2020. Primary outcome measures were Numeric Rating Scale (NRS), patient reported percent of pain relief, the Patient Health Questionnaire, the Patient Reported Outcome Measurement Information System (PROMIS) Global Health Physical and Mental Health score, and the Pain Disability Questionnaire.

RESULTS

A total of 219 individual patients underwent 261 CTFESI and were included in the analyses. The average subject age was 51.9 years (SD = 11.3) and 50.9 % were male. Following the intervention, average pain relief by NRS at 3 months, 6 months, 1 year, and 2 years was -4.07, -3.82, -4.20, and -4.45, respectively. The average functional improvement with PROMIS-GH physical at 3-months, 6-months, 1- year, and 2-years was 2.23, 2.35, 3.15, and 3.29, respectively.

CONCLUSIONS

Our results suggest that patients with cervical radiculopathy report significant pain relief and functional improvement following CTFESI. They can also report clinically important improvement in their health-related quality of life.

摘要

目的

评估经椎间孔颈椎硬膜外类固醇注射(CTFESI)治疗神经根性疼痛后疼痛和功能的改善情况。

设计

这是一项回顾性观察研究,研究对象为2013年12月至2020年12月在一家三级转诊中心由单一提供者在透视引导下接受经椎间孔颈椎硬膜外类固醇注射的患者。主要结局指标包括数字评定量表(NRS)、患者报告的疼痛缓解百分比、患者健康问卷、患者报告结局测量信息系统(PROMIS)全球健康身体和心理健康评分以及疼痛残疾问卷。

结果

共有219例个体患者接受了261次CTFESI,并纳入分析。受试者平均年龄为51.9岁(标准差=11.3),男性占50.9%。干预后,3个月、6个月、1年和2年时NRS评定的平均疼痛缓解分别为-4.07、-3.82、-4.20和-4.45。PROMIS-GH身体功能在3个月、6个月、1年和2年时的平均功能改善分别为2.23、2.35、3.15和3.29。

结论

我们的结果表明,颈椎神经根病患者在接受CTFESI后报告疼痛明显缓解且功能得到改善。他们还报告了与健康相关的生活质量有临床意义的改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f851/11372913/030f4ff275f5/gr1.jpg

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