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聚甲基丙烯酸甲酯增强型开窗椎弓根螺钉固定治疗低骨质量患者:病例系列及文献复习。

Polymethylmethacrylate-augmented fenestreted pedicle-screw fixation in low bone quality patients: a case series and literature review.

机构信息

Department of Oncologic and Degenerative Spine Surgery, IRCCS Istituto Ortopedico Rizzoli - Bologna, Italy.

Second Orthopedic Division, Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa, Pisa, Italy.

出版信息

J Biol Regul Homeost Agents. 2018 Nov-Dec;32(6 Suppl. 1):71-76.

Abstract

The use of pedicle screws in low bone quality patients implicates risks of secondary implant loosening for grip lack. In fact, the result is a reduced mechanical stability at bone-screw interface and consequently an increased chance of pullout and hardware failure. Augmentation techniques have been described for many years and fenestrated screws that allow cement injection is one of them. This is a retrospective observational study of patients treated at our department with polymethylmethacrylate- (PMMA) augmented fenestrated screws. Indications for posterior instrumentation were traumatic fracture in osteoporotic spine, oncological disease, post-traumatic deformity, degenerative disease, revision surgery and sickle cell disease fractures. Implant stability was evaluated with X-Rays and CT scan performed 3 days after surgery and every 3 months during the follow-up. Accuracy of screw placement was evaluated with Heary classification. Fifty-three surgical treatments in 52 patients were performed and 247 PMMA augmented fenestrated screws were placed. According to the Heary classification, 96.21% resulted Grade I, 1.8% Grade II, 2% Grade IV. A total of 17 complications occurred. Fenestrated screw augmentation should be performed in selected patients in whom the bone quality is insufficient to guarantee implant stability. These screws may result useful in complex cases as revision surgeries, osteoporosis and tumour affections where bone quality is highly compromised.

摘要

在骨质量较差的患者中使用椎弓根螺钉会因抓握不足而导致二次植入物松动的风险。事实上,这会导致骨-螺钉界面的机械稳定性降低,从而增加拔出和硬件故障的机会。多年来已经描述了许多增强技术,其中一种是允许注射水泥的带孔螺钉。这是对在我们部门接受聚甲基丙烯酸甲酯(PMMA)增强带孔螺钉治疗的患者进行的回顾性观察研究。后路器械固定的适应证为骨质疏松性脊柱创伤性骨折、肿瘤性疾病、创伤后畸形、退行性疾病、翻修手术和镰状细胞病骨折。术后 3 天和随访期间每 3 个月通过 X 射线和 CT 扫描评估植入物稳定性。螺钉放置的准确性采用 Heary 分类进行评估。对 52 名患者的 53 例手术进行了评估,并放置了 247 个 PMMA 增强带孔螺钉。根据 Heary 分类,96.21%为Ⅰ级,1.8%为Ⅱ级,2%为Ⅳ级。共发生 17 例并发症。在骨质量不足以保证植入物稳定性的情况下,应在选定的患者中进行带孔螺钉增强。这些螺钉在复杂病例中可能会很有用,例如翻修手术、骨质疏松症和肿瘤病变,这些情况下骨质量高度受损。

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