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伴有纤毛异常的卡塔格内综合征。

Kartagener syndrome with abnormalities of cilia.

作者信息

Lupin A J, Misko G J

出版信息

J Otolaryngol. 1978 Apr;7(2):95-102.

PMID:306444
Abstract

Kartagener syndrome of sinusitis, bronchiectasis and situs inversus has been so called since his classical description in 1933. This report presents two further cases, a brother and sister. They were extensively studied and the findings are reported. A unique finding was that in both patients, both in the maxillary sinuses and in the bronchi, abnormal cilia were discovered on electron microscopy. After a search of the literature the authors conclude that this finding is probably congenital rather than acquired and may explain the development of the sinusitis and bronchiectasis.

摘要

自1933年对鼻窦炎、支气管扩张和内脏转位三联征进行经典描述以来,该综合征便被称为卡塔格内综合征。本报告介绍了另外两例患者,为一对兄妹。对他们进行了广泛研究并报告了研究结果。一个独特的发现是,在这两名患者的上颌窦和支气管中,电子显微镜检查均发现了异常纤毛。作者在查阅文献后得出结论,这一发现可能是先天性的而非后天获得的,并且可能解释了鼻窦炎和支气管扩张的发病机制。

相似文献

1
Kartagener syndrome with abnormalities of cilia.伴有纤毛异常的卡塔格内综合征。
J Otolaryngol. 1978 Apr;7(2):95-102.
2
The Kartagener syndrome--an electron microscopic studies of biopsied mucosa.
Rocz Akad Med Bialymst. 1997;42 Suppl 2:12-4.
3
[Are ciliary abnormalities always present in Kartagener's syndrome? A study of 16 patients].[卡塔格内综合征中纤毛异常是否总是存在?对16例患者的研究]
Ann Otolaryngol Chir Cervicofac. 1989;106(6):302-5.
4
Abnormalities of cilia and chronic sinusitis.纤毛异常与慢性鼻窦炎。
Rhinology. 1987 Mar;25(1):57-62.
5
[How useful is the ultrastructural study of the cilia of the respiratory tract in the diagnosis of an immotile cilia syndrome?].[呼吸道纤毛超微结构研究在诊断纤毛不动综合征中具有多大作用?]
Schweiz Med Wochenschr. 1984 May 5;114(18):610-9.
6
[Changes in the structure of the cilia of the ciliated epithelium of the bronchi in Kartagener's syndrome in children].
Arkh Patol. 1986;48(5):64-8.
7
[The ultrastructure of the ciliary epithelium in patients with the Zivert-Kartagener syndrome, bronchiectasis and cystic hypoplasia of the lungs].[齐韦特-卡塔格内综合征、支气管扩张及肺囊性发育不全患者睫状体上皮的超微结构]
Arkh Patol. 1989;51(10):10-7.
8
[Observation of nasal mucosal cilia ultrastructure of Kartagener's syndrome].[卡塔格内综合征鼻黏膜纤毛超微结构观察]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 2001 Oct;36(5):323-5.
9
The immotile cilia syndrome: phase contrast light microscopy, scanning and transmission electron microscopy.
Pediatrics. 1980 Apr;65(4):698-702.
10
[Ciliary immotility syndrome without situs inversus in 2 children].
Pediatrie. 1982 Dec;37(8):573-8.

引用本文的文献

1
An interspecies heart-to-heart: Using to uncover the genetic basis of congenital heart disease.种间心连心:利用(此处原文“Using”后缺少内容)揭示先天性心脏病的遗传基础。
Curr Pathobiol Rep. 2017 Jun;5(2):187-196. doi: 10.1007/s40139-017-0142-x. Epub 2017 May 6.
2
Variations in the ultrastructure of human nasal cilia including abnormalities found in retinitis pigmentosa.人类鼻纤毛超微结构的变异,包括在视网膜色素变性中发现的异常。
J Clin Pathol. 1980 Apr;33(4):327-35. doi: 10.1136/jcp.33.4.327.
3
An ultrastructural study of primary cilia, abnormal cilia and ciliary knobs from the ciliated cells of the guinea-pig trachea.
豚鼠气管纤毛细胞的初级纤毛、异常纤毛和纤毛小结的超微结构研究
Cell Tissue Res. 1981;220(4):685-97. doi: 10.1007/BF00210455.
4
Genetical and ultrastructural aspects of the immotile-cilia syndrome.不动纤毛综合征的遗传学和超微结构方面
Am J Hum Genet. 1981 Nov;33(6):852-64.