Klein G, Thumb N
Rehabilitations-zentrum für rheumatische Erkrankungen, Ludwig-Boltzmann-Institut für Rehabilitation interner Erkrankungen, Saalfelden.
Acta Med Austriaca. 1988;15(5):130-4.
Approximately a quarter of polyarthritis in the elderly is beginning with a single- or oligo-articular attack of big joints. The first attack of the shoulder joints is noticed especially in men. Most of the patients with rheumatoid arthritis in the elderly have a gradually progressive course. There is often showed a very high blood sedimentation rate (BSR); rheumatoid factor is rare. Generally there is a strongly marked osteoporosis. The success of therapy with disease modifying agents is comparable with that of younger patients with rheumatoid arthritis, but there is a smaller tolerance to gold and D-penicillamine. In some non-steroidal anti-rheumatic drugs a lower dosage is recommended.
老年人约四分之一的多关节炎起病时为大关节的单关节或少关节发作。肩关节首发尤其多见于男性。老年类风湿关节炎患者大多病程呈渐进性。常表现为血沉（ESR）极高；类风湿因子少见。一般有明显的骨质疏松。改善病情药物治疗的成功率与年轻类风湿关节炎患者相当，但对金制剂和D-青霉胺的耐受性较小。在某些非甾体类抗风湿药中，建议采用较低剂量。
