Doose H, Baier W K
Department of neuropediatrics, University of Kiel, Federal Republic of Germany.
Brain Dev. 1988;10(6):347-54. doi: 10.1016/s0387-7604(88)80091-3.
Rhythmic theta activity maximally expressed in the parietobasal leads is a characteristic interictal EEG pattern in infants and children with primarily generalized "corticoreticular" seizures, including febrile convulsions. It is a strictly age-dependent electroencephalographic expression of a widespread genetic disposition to convulsions. If it coincides with photosensitivity, it leads to a considerable risk of spikes and waves. As epidemiological and family studies have shown, it is most likely polygenically determined and genetically independent of both photosensitivity and focal sharp waves. In epileptic patients the persisting expression of parietal theta rhythms beyond childhood bears prognostic significance. As one among many factors the "theta trait" is of importance in the "multifactorial" pathogenesis of epilepsy.
顶叶底部导联中最大程度表达的节律性θ活动是婴儿和儿童主要为全身性“皮质网状”癫痫发作（包括热性惊厥）的特征性发作间期脑电图模式。它是惊厥广泛遗传易感性的严格年龄依赖性脑电图表现。如果它与光敏性同时出现，则会导致出现棘波和慢波的相当大风险。正如流行病学和家族研究所示，它很可能是多基因决定的，并且在基因上与光敏性和局灶性尖波均无关。在癫痫患者中，顶叶θ节律在儿童期之后持续存在具有预后意义。作为众多因素之一，“θ特征”在癫痫的“多因素”发病机制中具有重要意义。
