Pulik M, Lida H, Blanchereau C
Unité d'Hématologie, Centre Hospitalier Victor Dupouy, Argenteuil.
Ann Otolaryngol Chir Cervicofac. 1988;105(7):543-7.
HIV virus infection is frequently accompanied by polyclonal or monoclonal lymphoid proliferations. The authors report the first case of a tumour of the cavum in a Haitian subject with HIV infection. This large tumour was associated with parotid swelling and a buccal and ocular sicca syndrome. Histological examination revealed Sjögren type of lympho-epithelial infiltration in the parotid and salivary glands. Biopsy of the cavum demonstrated lymphoid hyperplasia without a monoclonal component. There was no lymphoid proliferation outside of the ear, nose and throat region. The various benign and malignant lymphoid proliferations observed during HIV infection are recalled. Their pathophysiology is discussed: role of EBV in B cell lymphoid proliferations, specific cytotoxicity against cells infected by HIV in T8 proliferations.
人类免疫缺陷病毒（HIV）感染常伴有多克隆或单克隆淋巴细胞增殖。作者报告了首例海地HIV感染患者发生的咽腔肿瘤。这个大肿瘤伴有腮腺肿大及口腔和眼部干燥综合征。组织学检查显示腮腺和唾液腺有干燥综合征型淋巴上皮浸润。咽腔活检显示淋巴细胞增生，无单克隆成分。耳、鼻、喉区域外无淋巴细胞增殖。本文回顾了HIV感染期间观察到的各种良性和恶性淋巴细胞增殖情况。并讨论了它们的病理生理学：EB病毒在B细胞淋巴细胞增殖中的作用，T8增殖中对HIV感染细胞的特异性细胞毒性。
