Edwards Angelena, Peters Craig A
Children's Health System Texas, University of Texas Southwestern, Dallas, TX, USA.
F1000Res. 2019 Jan 8;8. doi: 10.12688/f1000research.16534.1. eCollection 2019.
Current management of vesicoureteral reflux (VUR) in children is the result of a steady albeit controversial evolution of data and thinking related to the clinical impact of VUR and urinary tract infection (UTI) in children, the value of clinical screening, and the relative impact of testing and interventions for VUR. While controversy continues, there is consensus on the importance of bladder dysfunction on VUR outcomes, the likelihood of VUR resolution, and the fact that not all children with VUR require active treatment. Early efforts to define risk stratification hold the most promise to provide more patient-specific treatment of UTI and VUR in children.
目前儿童膀胱输尿管反流(VUR)的管理是与儿童VUR和尿路感染(UTI)的临床影响、临床筛查的价值以及VUR检测和干预的相对影响相关的数据和思想稳步发展的结果,尽管这一发展存在争议。虽然争议仍在继续,但对于膀胱功能障碍对VUR结局的重要性、VUR自行缓解的可能性以及并非所有VUR儿童都需要积极治疗这一事实,已达成共识。早期确定风险分层的努力最有希望为儿童UTI和VUR提供更具个性化的治疗。