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德弗勒克斯封堵导致小儿尤因肉瘤出现显著肾功能丧失及化疗难题。

Obstruction from Deflux leading to significant kidney function loss and chemotherapeutic challenges in pediatric Ewing sarcoma.

作者信息

Martin Luke, Mehta Dipen, Morganstern Bradley

机构信息

Medical College of Georgia, Augusta, GA, USA.

Children's Hospital of Georgia | Wellstar MCG Health, Augusta, GA, USA.

出版信息

Urol Case Rep. 2024 Dec 5;58:102903. doi: 10.1016/j.eucr.2024.102903. eCollection 2025 Jan.

DOI:10.1016/j.eucr.2024.102903
PMID:39759586
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11699807/
Abstract

This report presents the case of an 8-year-old female with a history of vesicoureteral reflux (VUR) treated with Deflux injections, who developed Ewing sarcoma metastasized to the lungs. Despite the initial resolution of VUR following Deflux procedures, recurrent urinary tract infections prompted further evaluation revealing significant ureteral obstruction. Pre-chemotherapy workup included renal ultrasonography, nuclear medicine renal scan, and cystogram, identifying obstructive uropathy necessitating bilateral ureteral stent placement. This discussion encompasses the challenges of managing VUR, Deflux complications, and the importance of tailored follow-up protocols.

摘要

本报告介绍了一名8岁女性的病例，该患者有膀胱输尿管反流（VUR）病史，曾接受Deflux注射治疗，后发生了转移至肺部的尤因肉瘤。尽管在进行Deflux手术后VUR最初得到缓解，但反复的尿路感染促使进一步评估，结果显示存在严重的输尿管梗阻。化疗前的检查包括肾脏超声、核医学肾脏扫描和膀胱造影，确定存在梗阻性尿路病，需要双侧放置输尿管支架。本讨论涵盖了管理VUR的挑战、Deflux并发症以及定制化随访方案的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307f/11699807/959a1cb1c5c8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307f/11699807/934b116d2552/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307f/11699807/959a1cb1c5c8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307f/11699807/934b116d2552/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307f/11699807/959a1cb1c5c8/gr2.jpg

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本文引用的文献

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