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吸入1,1 - 二氟乙烷:心包积气的罕见病因。

Inhalation of 1-1-difluoroethane: A Rare Cause of Pneumopericardium.

作者信息

Faircloth Erika L, Soriano Jose, Phachu Deep

机构信息

Internal Medicine, University of Connecticut, Farmington, USA.

Internal Medicine, Saint Francis Hosptial and Medical Center, Hartford, USA.

出版信息

Cureus. 2018 Oct 27;10(10):e3503. doi: 10.7759/cureus.3503.

DOI:10.7759/cureus.3503
PMID:30648044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6318142/
Abstract

We report a case of a 32-year-old man with a past medical history of ethanol use disorder who was brought in unresponsive after inhaling six to 10 cans of the computer cleaning product, Dust-Off. After regaining consciousness, he endorsed severe, pleuritic chest and anterior neck pain. Labs were notable for elevated cardiac enzymes, acute kidney injury, and his initial electrocardiogram (ECG) revealed a partial right bundle branch block with a prolonged corrected QT interval (QTc). On chest X-ray as well as chest computed tomography, the patient was found to have pneumomediastinum, pneumopericardium, and subcutaneous emphysema. The patient's course was uneventful and he was discharged home two days later after extensive substance abuse cessation counseling. Intentionally inhaling toxic substances, also known as "huffing," is a dangerous new trend with significant consequences that clinicians need to be aware of and suspect in young patients presenting with chest pain. We present a rare case of pneumopericardium induced by inhalation of Dust-Off (1-1-difluoroethane).

摘要

我们报告一例32岁男性,有乙醇使用障碍病史,吸入6至10罐电脑清洁产品“除尘气”(Dust-Off)后被送来时已无反应。恢复意识后,他主诉有严重的胸膜炎性胸痛和前颈部疼痛。实验室检查结果显示心肌酶升高、急性肾损伤,其初始心电图(ECG)显示不完全性右束支传导阻滞伴校正QT间期(QTc)延长。胸部X线及胸部计算机断层扫描显示,患者有纵隔气肿、心包积气和皮下气肿。患者病情平稳,在接受广泛的药物滥用戒断咨询后,两天后出院。故意吸入有毒物质,也称为“嗅吸”,是一种危险的新趋势,会带来严重后果,临床医生需要对出现胸痛的年轻患者有所警惕并进行怀疑。我们报告一例罕见的因吸入“除尘气”(1-1-二氟乙烷)导致心包积气的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fcd/6318142/7204ac8a6e82/cureus-0010-00000003503-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fcd/6318142/c0dc4e93a7e3/cureus-0010-00000003503-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fcd/6318142/7204ac8a6e82/cureus-0010-00000003503-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fcd/6318142/c0dc4e93a7e3/cureus-0010-00000003503-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fcd/6318142/7204ac8a6e82/cureus-0010-00000003503-i02.jpg

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本文引用的文献

1
Inhaling Difluoroethane Computer Cleaner Resulting in Acute Kidney Injury and Chronic Kidney Disease.吸入二氟乙烷电脑清洁剂导致急性肾损伤和慢性肾脏病
Case Rep Nephrol. 2018 Jun 7;2018:4627890. doi: 10.1155/2018/4627890. eCollection 2018.
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Skeletal Fluorosis Due To Inhalation Abuse of a Difluoroethane-Containing Computer Cleaner.因滥用含二氟乙烷的电脑清洁剂吸入导致的骨氟中毒
J Bone Miner Res. 2017 Jan;32(1):188-195. doi: 10.1002/jbmr.2923. Epub 2016 Oct 14.
3
Inhalant-Abuse Myocarditis Diagnosed by Cardiac Magnetic Resonance.
通过心脏磁共振诊断的吸入性药物滥用性心肌炎
Tex Heart Inst J. 2016 Jun 1;43(3):246-8. doi: 10.14503/THIJ-14-4919. eCollection 2016 Jun.
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Cardiomyopathy from 1,1-Difluoroethane Inhalation.吸入1,1 - 二氟乙烷所致的心肌病
Cardiovasc Toxicol. 2016 Oct;16(4):370-3. doi: 10.1007/s12012-015-9348-5.
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Pneumopericardium resulting in cardiac tamponade.导致心脏压塞的心包积气。
Ann Thorac Surg. 1984 Jun;37(6):511-8. doi: 10.1016/s0003-4975(10)61146-0.