Calhoun Kristen, Wattenbarger Laura, Burns Ethan, Hatcher Courtney, Patel Amol, Badam Manjulatha, Khan Abdul-Jabbar
Texas A&M College of Medicine, The Methodist Hospital at Houston, 6565 Fannin Street, West Pavilion, Houston, TX 77030, USA.
Houston Methodist Hospital, 6550 Fannin Street, Suite 1101, Smith Tower, Houston, TX 77030, USA.
Case Rep Nephrol. 2018 Jun 7;2018:4627890. doi: 10.1155/2018/4627890. eCollection 2018.
Difluoroethane is the active ingredient in various computer cleaners and is increasingly abused by teenagers due to its ease of access, quick onset of euphoric effects, and lack of detectability on current urine drug screens. The substance has detrimental effects on various organ systems; however, its effects on the kidneys remain largely unreported. The following case report adds new information to the developing topic of acute kidney injury in patients abusing difluoroethane inhalants. In addition, it is one of the first to show a possible relationship between prolonged difluoroethane abuse and the development of chronic kidney disease in the absence of other predisposing risk factors.
二氟乙烷是各种电脑清洁剂中的活性成分，由于其易于获取、能迅速产生欣快感且目前的尿液药物筛查无法检测到，正越来越多地被青少年滥用。该物质对各种器官系统都有有害影响；然而，其对肾脏的影响在很大程度上仍未被报道。以下病例报告为滥用二氟乙烷吸入剂患者急性肾损伤这一不断发展的话题增添了新信息。此外，这是首批显示在没有其他诱发风险因素的情况下，长期滥用二氟乙烷与慢性肾脏病发展之间可能存在关联的报告之一。
