Gajjar Kushani, Balakumaran Kathir, Kim Agnes S
Internal Medicine, University of Connecticut Health Center, Farmington, USA.
Cardiology, University of Connecticut Health Center, Farmington, USA.
Cureus. 2018 Oct 29;10(10):e3517. doi: 10.7759/cureus.3517.
Pazopanib is a tyrosine kinase inhibitor used for the treatment of advanced renal cell carcinoma and advanced soft tissue sarcoma. We describe a case report of a patient with spindle cell sarcoma who developed severe left ventricular systolic dysfunction after starting pazopanib therapy with subsequent recovery of left ventricular ejection fraction upon stopping therapy.