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Reversible Left Ventricular Systolic Dysfunction Secondary to Pazopanib.

作者信息

Gajjar Kushani, Balakumaran Kathir, Kim Agnes S

机构信息

Internal Medicine, University of Connecticut Health Center, Farmington, USA.

Cardiology, University of Connecticut Health Center, Farmington, USA.

出版信息

Cureus. 2018 Oct 29;10(10):e3517. doi: 10.7759/cureus.3517.

Abstract

Pazopanib is a tyrosine kinase inhibitor used for the treatment of advanced renal cell carcinoma and advanced soft tissue sarcoma. We describe a case report of a patient with spindle cell sarcoma who developed severe left ventricular systolic dysfunction after starting pazopanib therapy with subsequent recovery of left ventricular ejection fraction upon stopping therapy.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c220/6318145/6144b6acff3f/cureus-0010-00000003517-i01.jpg

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