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微血管减压术联合纵行神经切断术治疗复发性三叉神经痛的效果及术后复发原因探讨

Effects of Microvascular Decompression Plus Longitudinal Nerve Sectioning on Recurrent Trigeminal Neuralgia and Investigations of Postoperative Recurrence Causes.

作者信息

Cong Luo, Zhihua Cheng, Zhilin Guo, Huoniu Ou Yang

机构信息

Shanghai Jiao Tong University, School of Medicine, Shanghai Ninth People’s Hospital, Department of Neurosurgery, Shanghai, China.

出版信息

Turk Neurosurg. 2019;29(3):369-376. doi: 10.5137/1019-5149.JTN.23513-18.1.

DOI:10.5137/1019-5149.JTN.23513-18.1
PMID:30649792
Abstract

AIM

To investigate the causes of recurrent trigeminal neuralgia (RTN) and to evaluate the efficacy of microvascular decompression (MVD) plus longitudinal nerve sectioning (LNS) or LNS only for RTN patients who have undergone multiple procedures.

MATERIAL AND METHODS

Twenty one patients underwent MVD plus LNS or LNS only at our institute from June 2008 to December 2014. The patients were retrospectively reviewed and analyzed. The following data were collected: age, sex , treatment before surgery, pain severity and distribution, findings during surgery, immediate postoperative BNI (Barrow Neurological Institute score system), final follow-up BNI, complications and associated comorbidities.

RESULTS

Vascular compression, arachnoid adhesion and Teflon granulomas were the primary causes of RTN. After MVD plus LNS or LNS only treatments, almost all patients (19/21, 90.5%) reported pain relief after 36.1 months. Of these patients, 15 patients (71.4%) reported being pain-free (BNI score I) and 4 patients (19.1%) reported pain relief (BNI II-III). Two patients reported a pain level of BNI IV. However, almost all patients were left with some degree of numbness.

CONCLUSION

This study certified that vascular compression, arachnoid adhesion and Teflon granulomas were the reasons for RTN. MVD plus LNS or LNS only were both feasible therapeutic options, with good probabilities of success, especially after multiple neurodestructive procedures.

摘要

目的

探讨复发性三叉神经痛(RTN)的病因,并评估微血管减压术(MVD)联合纵行神经切断术(LNS)或单纯LNS对已接受多次手术的RTN患者的疗效。

材料与方法

2008年6月至2014年12月,21例患者在我院接受了MVD联合LNS或单纯LNS治疗。对患者进行回顾性分析。收集以下数据:年龄、性别、术前治疗、疼痛严重程度及分布、手术中的发现、术后即刻的巴罗神经学研究所(BNI)评分系统评分、最终随访时的BNI评分、并发症及合并症。

结果

血管压迫、蛛网膜粘连和聚四氟乙烯肉芽肿是RTN的主要病因。在接受MVD联合LNS或单纯LNS治疗后,几乎所有患者(19/21,90.5%)在36.1个月后报告疼痛缓解。其中,15例患者(71.4%)报告无痛(BNI评分I级),4例患者(19.1%)报告疼痛缓解(BNI II - III级)。2例患者报告疼痛程度为BNI IV级。然而,几乎所有患者都遗留有一定程度的麻木。

结论

本研究证实血管压迫、蛛网膜粘连和聚四氟乙烯肉芽肿是RTN的病因。MVD联合LNS或单纯LNS都是可行的治疗选择,成功概率较高,尤其是在多次神经毁损手术后。

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