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基于单像素成像的显微断层扫描技术。

Micro-tomography via single-pixel imaging.

作者信息

Peng Junzheng, Yao Manhong, Cheng Jiajian, Zhang Zibang, Li Shiping, Zheng Guoan, Zhong Jingang

出版信息

Opt Express. 2018 Nov 26;26(24):31094-31105. doi: 10.1364/OE.26.031094.

DOI:10.1364/OE.26.031094
PMID:30650700
Abstract

Tomographic imaging allows for the cross-sectional imaging of specimen, whereas single-pixel imaging can produce image only with a spatial non-resolved detector. Here we propose a compact tomographic imaging system combining single-pixel imaging. This approach uses a digital micromirror device (DMD) to encode the spatial information of specimen and employs an array of single-pixel detectors to record the light signals from different directions. For each single-pixel detector, we can retrieve an image of the specimen from a unique perspective angle. Based on the retrieved images, we can realize tomographic imaging, such as intensity images refocusing and three-dimensional (3D) differential-phase-contrast imaging, without mechanically scanning the specimen. Experimental results also demonstrate that the micro-tomographic images with 384×384 pixels can be simultaneously realized only with an array of 5×6 single-pixel detectors. Furthermore, due to the broad operational spectrum of the single-pixel detector, the proposed method is a good candidate to realize tomographic imaging with the non-visible light wavebands, such as terahertz and x-ray, thus it would open up opportunities in many life science and engineering fields.

摘要

断层成像能够对样本进行截面成像,而单像素成像仅能使用空间未分辨探测器生成图像。在此,我们提出一种结合单像素成像的紧凑型断层成像系统。该方法使用数字微镜器件(DMD)对样本的空间信息进行编码,并采用单像素探测器阵列记录来自不同方向的光信号。对于每个单像素探测器,我们可以从独特的视角角度获取样本的图像。基于获取的图像,我们无需对样本进行机械扫描就能实现断层成像,如强度图像重聚焦和三维(3D)微分相衬成像。实验结果还表明,仅使用一个5×6的单像素探测器阵列就能同时实现384×384像素的微观断层图像。此外,由于单像素探测器的工作光谱范围广,所提出的方法是实现太赫兹和X射线等不可见光波段断层成像的理想选择,因此它将在许多生命科学和工程领域开辟机会。

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