Ma Qingmin, Fan Fang, Zhao Zhihua, Jia Zhiyang
Department of Ophthalmology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Exp Ther Med. 2019 Jan;17(1):525-530. doi: 10.3892/etm.2018.6963. Epub 2018 Nov 13.
The aim of the present study was to assess the curative effect of combined phacoemulsification, 23-gauge pars plana vitrectomy with Brilliant blue G-assisted limiting membrane peeling and gas tamponade in patients with coexisting idiopathic macular hole (IMH) and age-associated cataract. A total of 21 consecutive patients (21 eyes) with coexisting IMH and age-associated cataract were enrolled in the study. All patients were treated by 23-gauge microincision vitrectomy with internal limiting membrane peeling, gas tamponade and combined phacoemulsification. The pre-operative MH diameter, MH index and best-corrected visual acuity (BCVA), as well as events of post-operative MH closure and complications were recorded and analyzed. Anatomic closure of the MH was achieved in 19 eyes (90.4%) with a single surgery. The LogMAR BCVA value at 1 month after surgery and the final follow-up visit was significantly lower than the baseline value (P=0.0036 and P=0.0015, respectively). A significant correlation was identified between the MH index and the post-operative LogMAR BCVA (r=0.869; P<0.001). The combined technique applied in the present study produced favorable anatomic and functional results for patients with coexisting IMH and age-associated cataracts. The pre-operative MH size measured by optical coherence tomography may serve as a predictive factor for the LogMAR BCVA value following MH surgery.
本研究的目的是评估超声乳化术、23G 经睫状体平坦部玻璃体切除术联合亮蓝 G 辅助内界膜剥除及气体填充治疗特发性黄斑裂孔(IMH)合并年龄相关性白内障患者的疗效。本研究共纳入 21 例连续的 IMH 合并年龄相关性白内障患者(21 只眼)。所有患者均接受 23G 微切口玻璃体切除术联合内界膜剥除、气体填充及超声乳化术治疗。记录并分析术前黄斑裂孔直径、黄斑裂孔指数及最佳矫正视力(BCVA),以及术后黄斑裂孔闭合情况和并发症。19 只眼(90.4%)通过单次手术实现了黄斑裂孔的解剖学闭合。术后 第 1 个月及末次随访时的 LogMAR BCVA 值均显著低于基线值(分别为 P = 0.0036 和 P = 0.0015)。黄斑裂孔指数与术后 LogMAR BCVA 之间存在显著相关性(r = 0.869;P < 0.001)。本研究中应用的联合技术对 IMH 合并年龄相关性白内障患者产生了良好的解剖学和功能学效果。术前通过光学相干断层扫描测量的黄斑裂孔大小可作为黄斑裂孔手术后 LogMAR BCVA 值的预测因素。