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硅油填充治疗特发性黄斑裂孔

Treatment of idiopathic macular hole with silicone oil tamponade.

作者信息

Ivanovska-Adjievska Biljana, Boskurt Salih, Semiz Faruk, Yuzer Hakan, Dimovska-Jordanova Vesna

机构信息

European Eye Hospital, Skopje, Macedonia.

出版信息

Clin Ophthalmol. 2012;6:1449-54. doi: 10.2147/OPTH.S33902. Epub 2012 Aug 6.

Abstract

PURPOSE

We analyzed the anatomical and visual outcomes after surgical treatment of idiopathic macular holes with pars plana vitrectomy, internal limiting membrane (ILM) peeling using Brilliant Blue dye, and silicone oil tamponade without postoperative posturing.

METHODS

This was a retrospective interventional study of 10 eyes in eight patients who underwent surgical treatment of idiopathic macular holes using pars plana vitrectomy, ILM peeling using Brilliant Blue dye, and silicone oil tamponade without postoperative posturing. The preoperative staging of macular holes and postoperative anatomic outcomes were assessed using spectral-domain optical coherence tomography.

RESULTS

All patients were women with a mean age of 66.86 ± 4.8 years. In two patients, bilateral macular holes were present and both eyes were operated on. Stage 2 macular hole was diagnosed in three eyes, three eyes had stage 3, and four eyes had stage 4 macular holes. Anatomical success and closure of the macular hole was achieved in nine eyes (90%) after one operation. In one eye, the macular hole was closed after reoperation. The preoperative mean best-corrected visual acuity (BCVA) was 0.15 decimal units (0.8 logMAR units). Until the end of the follow-up period, BCVA was 0.25 decimal units (0.6 logMAR units). Visual acuity was improved in seven patients (70%). In two patients (20%), visual acuity remained at the same level, and in one eye (10%), visual acuity decreased. Postoperatively, all patients reported a significant reduction of metamorphopsia.

CONCLUSION

Initial results after 20G pars plana vitrectomy with peeling of the ILM, use of dye (Brilliant Blue), and tamponade with silicone oil without postoperative posturing gave good anatomical and functional outcome in terms of visual acuity and reduction of metamorphopsia. Taking into account the age of the patients, this method, which does not require prolonged postoperative face-down posturing, was well tolerated by the patients. Because the anatomical and visual outcome as well as the rate of postoperative complications are comparable to those when gas is used as a tamponading agent, silicone oil tamponade can also be safely used as a first option in surgery of macular holes. However, a longer period of follow-up of the operated eyes, as well as a larger group of operated eyes, will be required to identify long-term outcomes of this surgical treatment.

摘要

目的

我们分析了采用玻璃体切除术、使用亮蓝染料剥除内界膜(ILM)以及硅油填充且术后不采取体位的手术方法治疗特发性黄斑裂孔后的解剖学和视觉效果。

方法

这是一项回顾性干预研究,纳入了8例患者的10只眼,这些患者采用玻璃体切除术、使用亮蓝染料剥除ILM以及硅油填充且术后不采取体位的手术方法治疗特发性黄斑裂孔。使用光谱域光学相干断层扫描评估黄斑裂孔的术前分期和术后解剖学效果。

结果

所有患者均为女性,平均年龄66.86±4.8岁。2例患者存在双侧黄斑裂孔,双眼均接受了手术。3只眼诊断为2期黄斑裂孔,3只眼为3期,4只眼为4期黄斑裂孔。一次手术后,9只眼(90%)实现了解剖学成功及黄斑裂孔闭合。1只眼在再次手术后黄斑裂孔闭合。术前平均最佳矫正视力(BCVA)为0.15(对数最小分辨角为0.8)。直至随访期结束,BCVA为0.25(对数最小分辨角为0.6)。7例患者(70%)视力得到改善。2例患者(20%)视力保持不变,1只眼(10%)视力下降。术后,所有患者均报告变形视显著减轻。

结论

20G玻璃体切除术联合ILM剥除、使用染料(亮蓝)以及硅油填充且术后不采取体位的初步结果在视力和减轻变形视方面产生了良好的解剖学和功能效果。考虑到患者年龄,这种无需长时间术后俯卧位的方法患者耐受性良好。由于解剖学和视觉效果以及术后并发症发生率与使用气体作为填充剂时相当,硅油填充也可安全地作为黄斑裂孔手术的首选。然而,需要对手术眼进行更长时间的随访以及纳入更大规模的手术眼组来确定这种手术治疗的长期效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0be/3460698/e7c753ca404f/opth-6-1449f1.jpg

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