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NGM282: a step forward in the nonalcoholic steatohepatitis treatment landscape?

作者信息

Valenti Luca, Nobili Valerio

机构信息

Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milano, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

Hepatology, Gastroenterology and Nutrition Unit, IRCCS "Bambino Gesù" Children's Hospital, Rome, Italy.

出版信息

Hepatobiliary Surg Nutr. 2018 Dec;7(6):484-486. doi: 10.21037/hbsn.2018.10.03.

Abstract
摘要

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Hepatic fat as clinical outcome and therapeutic target for nonalcoholic fatty liver disease.
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Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver.
J Intern Med. 2018 Apr;283(4):356-370. doi: 10.1111/joim.12719. Epub 2017 Dec 27.
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Nuclear receptors and cholesterol metabolism in the intestine.
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Separating Tumorigenicity from Bile Acid Regulatory Activity for Endocrine Hormone FGF19.
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