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急性传染性肝炎的血清流行病学(作者译)

[Seroepidemiology of acute infectious hepatitis (author's transl)].

作者信息

Müller R, Willers H, Höpken W

出版信息

MMW Munch Med Wochenschr. 1978 Apr 14;120(15):517-20.

PMID:306523
Abstract

Hbs-Ag, anti-Hbs, anti-Hbc and anti-HA were determined and the concentration of IgM measured in the sera of cases of acute infectious hepatitis which occurred in the Hannover area in 1975. Although there was a high degree of contamination with hepatitis A virus among the population, acute infectious hepatitis A was rare (n = 56). The hepatitis A virus is principally transmitted by contact with infection or while traveling in southern Europe. The greatest part of infectious hepatitis is due to hepatitis virus B (n = 211). Non-A, non-B hepatitis was less frequently observed (n = 62). A high percentage of patients with serum hepatitis and non-A, non-B hepatitis gave a history of parenteral exposure to possibly infectious material.

摘要

检测了1975年发生在汉诺威地区的急性传染性肝炎病例血清中的乙肝表面抗原(Hbs-Ag)、乙肝表面抗体(anti-Hbs)、乙肝核心抗体(anti-Hbc)和甲型肝炎抗体(anti-HA),并测定了IgM的浓度。尽管该地区人群中甲型肝炎病毒污染程度很高,但急性甲型传染性肝炎却很罕见(n = 56)。甲型肝炎病毒主要通过接触感染或在南欧旅行时传播。大部分传染性肝炎是由乙型肝炎病毒引起的(n = 211)。非甲非乙型肝炎较少见(n = 62)。血清性肝炎和非甲非乙型肝炎患者中,很大比例有经肠道外接触可能感染性物质的病史。

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