环状 RNA 在心血管疾病中的作用。
Role of circular RNAs in cardiovascular diseases.
机构信息
Department of Cardiology, Daping Hospital, Third Military Medical University, Chongqing 400042, P.R. China.
出版信息
Exp Biol Med (Maywood). 2019 Feb;244(2):73-82. doi: 10.1177/1535370218822988. Epub 2019 Jan 17.
Abstract
Circular RNAs are important regulators of multiple biological processes such as organogenesis and oncogenesis. Although the bulk of concerning studies focused on revealing their diversified roles in various types of cancers, reports began to accumulate in cardiovascular field these days. We summarize circular RNAs implicated in cardiovascular diseases, aiming to highlight the advances in the knowledge of such diseases and their potential of being promising target for diagnosis and therapy.
摘要
环状 RNA 是多种生物学过程（如器官发生和致癌作用）的重要调节因子。尽管大多数相关研究都集中在揭示它们在各种类型癌症中的多样化作用，但最近在心血管领域的报道开始增多。我们总结了与心血管疾病相关的环状 RNA，旨在强调这些疾病知识的进展及其作为诊断和治疗有希望的靶点的潜力。
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