From the Institute of Diagnostic and Interventional Radiology (H.H., X.Z., J.Z., Y.L.).
From the Institute of Diagnostic and Interventional Radiology (H.H., X.Z., J.Z., Y.L.)
AJNR Am J Neuroradiol. 2019 Feb;40(2):313-318. doi: 10.3174/ajnr.A5946. Epub 2019 Jan 17.
Carotid web was recognized as a cause of ischemic stroke. We sought to determine the clinical and imaging profiles of patients with a carotid web as well as its association with TIA.
A retrospective review of carotid CT angiography studies and brain MR imaging in patients with TIA during the past 3 years ( = 135) was performed to determine the presence of carotid webs by 2 experienced neuroradiologists according to previously published criteria. Demographics and clinical and imaging characteristics are shown by descriptive statistics for patients with an identified carotid web. The agreement in the detection of carotid webs between 2 neuroradiologists was examined using κ statistics.
There were 12 (8.9%) carotid webs at the symptomatic bifurcation and 1 carotid web (0.7%) at the asymptomatic bifurcation, and no hyperintensity was seen on DWI of these 12 patients. Eight of these 12 (75%) patients with a carotid web were women. None of the 12 patients with a carotid web had major risk factors or other causes of TIA. Fair-to-good interobserver agreement (κ = 0.87) was seen for diagnosing a carotid web with CT angiography. The rate (10/12, 83.3%) of short-term recurrent episodes of TIA in patients with TIA with a carotid web was significantly higher than that of patients without a carotid web (15/123, 12.2%) ( < .001).
The incidence of carotid web in patients with TIA was 8.9%. There is an association between carotid web and patients with TIA without other identified risks. Carotid web may be an underestimated risk factor for TIA.
颈动脉壁是缺血性卒中的一个病因。我们旨在确定颈动脉壁患者的临床和影像特征,以及其与 TIA 的关联。
对过去 3 年(= 135)接受 TIA 治疗的患者的颈动脉 CT 血管造影研究和脑部磁共振成像进行回顾性分析,根据先前发表的标准,由 2 名有经验的神经放射科医生确定颈动脉壁的存在。对于确定存在颈动脉壁的患者,通过描述性统计方法显示人口统计学、临床和影像学特征。采用κ统计检验 2 名神经放射科医生在检测颈动脉壁方面的一致性。
在有症状的分叉处有 12 例(8.9%)颈动脉壁,在无症状的分叉处有 1 例(0.7%)颈动脉壁,这 12 例患者的 DWI 未见高信号。这 12 例颈动脉壁患者中有 8 例(75%)为女性。这 12 例颈动脉壁患者均无主要危险因素或其他 TIA 病因。使用 CT 血管造影诊断颈动脉壁时,观察者间的一致性为中等至良好(κ=0.87)。在有 TIA 合并颈动脉壁的患者中,短期复发性 TIA 发作的发生率(10/12,83.3%)明显高于无颈动脉壁的患者(15/123,12.2%)(<0.001)。
在 TIA 患者中,颈动脉壁的发生率为 8.9%。颈动脉壁与无其他明确风险的 TIA 患者之间存在关联。颈动脉壁可能是 TIA 的一个被低估的危险因素。