Dao Kimberly A, Tadros Sameh, Chan Serena, Poremski Pamela M, Squires Judy H
Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Department of Radiology, Boston Children's Hospital, Boston, MA, USA.
Pediatr Radiol. 2019 May;49(5):632-637. doi: 10.1007/s00247-018-04336-7. Epub 2019 Jan 17.
Changes that occur in the remaining ovary after contralateral oophorectomy are not well described.
To determine average ovarian volume in pediatric patients after contralateral oophorectomy compared to age-matched controls with two normal ovaries.
We performed a retrospective review of ultrasound examinations and electronic medical records of patients ages 0-18 years who had unilateral oophorectomy from 2000 to 2017 (n=64). We used 384 consecutive normal age-matched ovaries for comparison, analyzing mean ovarian volumes.
Higher mean ovarian volume (mL) was observed in patients who had oophorectomy compared to controls in the first decade of life (P<0.003) and second decade of life (P<0.0003). Higher mean ovarian volume was seen in both premenarchal and menstruating patients with prior oophorectomy when compared to controls (P<0.05 and P<0.0001, respectively). When comparing volume during menstrual cycle, we saw higher mean ovarian volumes in the oophorectomy group compared to the control group for the follicular (P<0.0001), pre-ovulatory (P=0.0005) and luteal phases (P<0.0003). We provide an updated reference of normal ovarian volumes for pediatric patients, with values similar to those already reported in the literature.
Ovarian volume is higher in pediatric patients with one normal ovary following contralateral oophorectomy. The provided normative volumes can be used in evaluating these patients.
对侧卵巢切除术后，留存卵巢所发生的变化尚无详尽描述。
与双侧卵巢均正常的年龄匹配对照组相比，确定对侧卵巢切除术后儿科患者的平均卵巢体积。
我们对2000年至2017年间接受单侧卵巢切除术的0至18岁患者的超声检查和电子病历进行了回顾性分析（n = 64）。我们使用384个连续的年龄匹配的正常卵巢作为对照，分析平均卵巢体积。
与对照组相比，在生命的第一个十年（P < 0.003）和第二个十年（P < 0.0003）中，接受卵巢切除术的患者平均卵巢体积（mL）更高。与对照组相比，既往接受过卵巢切除术的青春期前和月经来潮患者的平均卵巢体积均更高（分别为P < 0.05和P < 0.0001）。在比较月经周期中的体积时，我们发现卵巢切除组在卵泡期（P < 0.0001）、排卵前期（P = 0.0005）和黄体期（P < 0.0003）的平均卵巢体积高于对照组。我们提供了儿科患者正常卵巢体积的最新参考值，其值与文献中已报道的值相似。
对侧卵巢切除术后，仅有一侧正常卵巢的儿科患者的卵巢体积更大。所提供的标准体积可用于评估这些患者。
