Department of Child and Adolescent Psychiatry, Aarhus University Hospital Psychiatry, Palle Juul-Jensens Boulevard 175, Entrance K, 8200, Århus, Denmark.
Faculty of Psychology, University of Iceland, Reykjavík, Iceland.
Eur Child Adolesc Psychiatry. 2019 Aug;28(8):1097-1106. doi: 10.1007/s00787-019-01276-x. Epub 2019 Jan 17.
Hoarding, common in pediatric obsessive-compulsive disorder (OCD), has specific clinical correlates and is associated with poor prognosis. However, there are few studies of hoarding in pediatric OCD. This study estimates the occurrence of hoarding symptoms in a sample of children and adolescents with OCD, investigating possible differences in demographic and clinical variables between pediatric OCD with and without hoarding symptoms. Furthermore, the study investigates whether hoarding symptoms predict poorer treatment outcomes after cognitive behavioral therapy (CBT). The study sample comprised 269 children and adolescents with OCD, aged 7-17 years, from Denmark, Sweden, and Norway, who were all included in the Nordic long-term obsessive-compulsive disorder Treatment Study. All had an OCD diagnosis according to the DSM-IV and were treated with 14 weekly sessions of manualized, exposure-based CBT. Hoarding symptoms and OCD severity were assessed with the Children's Yale-Brown Obsessive-Compulsive Scale and group differences in treatment outcome were analyzed using linear mixed-effect modelling. Seventy-two patients (26.8%) had one or more symptoms of hoarding. Comorbid tic disorders (p = 0.005) and indecision (p = 0.024) were more prevalent among those with hoarding symptoms than those without hoarding symptoms. In addition, youth with hoarding symptoms had a different OCD symptom profile. Having symptoms of hoarding did not affect CBT outcome (p = 0.933). Results from the study suggest that CBT is equally effective for those with and without hoarding-related OCD.
囤积症在儿科强迫症(OCD)中较为常见,具有特定的临床相关性,且与预后不良有关。然而,针对儿科 OCD 中囤积症的研究较少。本研究评估了囤积症状在 OCD 患儿和青少年样本中的发生情况,调查了具有和不具有囤积症状的儿科 OCD 在人口统计学和临床变量方面的差异。此外,本研究还探讨了囤积症状是否能预测认知行为疗法(CBT)后的治疗效果较差。研究样本包括来自丹麦、瑞典和挪威的 269 名 7-17 岁的 OCD 儿童和青少年,他们都被纳入北欧长期 OCD 治疗研究。所有患者均根据 DSM-IV 诊断为 OCD,并接受 14 周的基于暴露的手册化 CBT。采用儿童耶鲁-布朗强迫症量表评估囤积症状和 OCD 严重程度,并使用线性混合效应模型分析治疗结果的组间差异。72 名患者(26.8%)存在 1 种或多种囤积症状。具有囤积症状的患者比不具有囤积症状的患者更易合并 tic 障碍(p=0.005)和犹豫不决(p=0.024)。此外,具有囤积症状的青少年具有不同的 OCD 症状特征。具有囤积症状并不会影响 CBT 结果(p=0.933)。本研究结果表明,CBT 对具有和不具有囤积相关 OCD 的患者同样有效。