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儿童强迫症中健康焦虑症状:患者特征及其对治疗效果的影响。

Health anxiety symptoms in pediatric obsessive-compulsive disorder: patient characteristics and effect on treatment outcome.

机构信息

Department of Child and Adolescent Psychiatry, Aarhus University Hospital, Aarhus, Denmark.

Faculty of Psychology, University of Iceland, Reykjavik, Iceland.

出版信息

Eur Child Adolesc Psychiatry. 2022 Aug;31(8):1317-1328. doi: 10.1007/s00787-021-01774-x. Epub 2021 Apr 16.

Abstract

The aim was to explore the potential clinical role of health anxiety (HA) symptoms in children and adolescents diagnosed with obsessive-compulsive disorder (OCD). The study investigated differences in demographic and various clinical variables between young people with OCD, with and without HA symptoms, and the effect of HA symptoms on overall OCD treatment outcome. The study sample comprised 269 children and adolescents with OCD (aged 7-17 years) from the large Nordic Long-term OCD Treatment Study. OCD symptoms and severity were assessed with The Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS), which includes one item regarding HA-like obsessions and one item regarding HA-like compulsions that were used to define the HA group. Several other instruments were used to assess comorbidity and other clinical aspects. All participants were treated with 14 weekly protocolled sessions of exposure-based cognitive behavioral therapy (CBT). HA symptoms were present in 31% of participants. Other anxiety symptoms and comorbid anxiety disorders were more prevalent among those with HA symptoms. These patients also presented with significantly more types of OCD symptoms. HA symptoms were reduced following OCD treatment with CBT and having HA symptoms did not affect CBT outcome. Results suggest that pediatric OCD with HA symptoms is characterized by more anxiety symptoms and a more heterogeneous OCD symptom profile. Standardized CBT seems equally effective in treating child and adolescent OCD with or without HA symptoms.Clinical trials registration: Nordic Long-term Obsessive-Compulsive Disorder Treatment Study: www.controlled-trials.com ; ISRCTN66385119.

摘要

目的在于探讨健康焦虑(HA)症状在诊断为强迫症(OCD)的儿童和青少年中的潜在临床作用。本研究调查了伴有和不伴有 HA 症状的 OCD 青少年在人口统计学和各种临床变量方面的差异,以及 HA 症状对整体 OCD 治疗结果的影响。研究样本包括来自大型北欧长期 OCD 治疗研究的 269 名患有 OCD 的儿童和青少年(年龄 7-17 岁)。使用儿童耶鲁-布朗强迫症量表(CY-BOCS)评估 OCD 症状和严重程度,该量表包括一个关于 HA 样强迫观念的项目和一个关于 HA 样强迫行为的项目,用于定义 HA 组。还使用了其他几种工具来评估共病和其他临床方面。所有参与者均接受了 14 周的基于暴露的认知行为疗法(CBT)方案治疗。31%的参与者存在 HA 症状。在伴有 HA 症状的患者中,其他焦虑症状和共患焦虑障碍更为常见。这些患者还表现出明显更多类型的 OCD 症状。HA 症状在接受 CBT 治疗 OCD 后得到缓解,并且存在 HA 症状不会影响 CBT 结果。结果表明,伴有 HA 症状的儿科 OCD 以更多的焦虑症状和更异质的 OCD 症状谱为特征。标准化的 CBT 似乎对治疗伴有或不伴有 HA 症状的儿童和青少年 OCD 同样有效。临床试验注册:北欧长期强迫症治疗研究:www.controlled-trials.com;ISRCTN66385119。

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