是否应该停止使用单剂量口服甲硝唑治疗女性滴虫病？
Is It Time to Stop Using Single-dose Oral Metronidazole for the Treatment of Trichomoniasis in Women?
机构信息
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA.
出版信息
Sex Transm Dis. 2019 May;46(5):e57-e59. doi: 10.1097/OLQ.0000000000000959.
Abstract
The 2015 Centers for Disease Control Sexually Transmitted Disease treatment guidelines currently recommend a single 2-g dose of oral metronidazole as the preferred regimen for treatment of trichomoniasis in human immunodeficiency virus (HIV)-negative women. Mounting recent evidence has shown that the 7-day oral metronidazole dosing regimen is more efficacious than the single 2-g dose. This commentary reviews the implications associated with these new data and discusses issues surrounding it that should be considered moving forward.
摘要
2015 年疾病控制与预防中心性传播疾病治疗指南目前建议对人类免疫缺陷病毒（HIV）阴性女性的滴虫病采用单次 2 克口服甲硝唑作为首选治疗方案。最近越来越多的证据表明，7 天口服甲硝唑给药方案比单次 2 克剂量更有效。本评论回顾了这些新数据的相关意义，并讨论了在向前推进时应考虑的相关问题。
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