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门诊小儿外科术后阿片类药物处方的趋势。

Trends in Postoperative Opioid Prescribing in Outpatient Pediatric Surgery.

机构信息

Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Drexel University, Philadelphia, Pennsylvania.

出版信息

Pain Med. 2019 Sep 1;20(9):1789-1795. doi: 10.1093/pm/pny284.

Abstract

OBJECTIVE

To determine trends in opioid prescribing for home use after pediatric outpatient surgery.

DESIGN

Retrospective analysis of a de-identified database.

SETTING

Multispecialty children's hospital and freestanding surgery centers.

PATIENTS, PARTICIPANTS: A total of 65,190 encounters of pediatric outpatient surgeries from 2013 through 2017 for nine different surgical specialties. Patients in the cardiothoracic service and nonpainful procedures were excluded.

MAIN

Outcome Measures. Incidence rate of prescribing, dose, number of doses available (i.e., duration of therapy), and maximum weight-based home opioid availability from 2013 to 2017. Additional independent variables included sex, age, weight, race/ethnicity, insurance type (private vs public), and surgical service.

RESULTS

The incidence rate of receiving a take-home opioid prescription at discharge ranged from 18% to 21% between 2013 and 2017, with no clear directional trend. Among patients prescribed opioids, however, the maximum available take-home dose steadily declined from 2013 through 2017 (P < 0.001). This was due to both a decrease in the number of doses prescribed (i.e., duration of treatment) and, beginning in 2015, the amount per dose. Females were more likely to receive an opioid than males, and patients with public insurance were more likely to receive an opioid than those with private insurance. Opioid prescribing was more likely in patients who did not disclose their ethnicity and those of ethnic minority compared with white patients (all P < 0.0001).

CONCLUSIONS

The rate of receiving a take-home opioid prescription and the dose prescribed remained stable from 2013 to 2017, but the duration of treatment steadily declined, and beginning in 2015, the amount per dose also decreased. Certain subgroups of patients were more likely to be prescribed opioids and will require further investigation and confirmation.

摘要

目的

确定小儿门诊手术后家庭使用阿片类药物处方的趋势。

设计

对去标识数据库进行回顾性分析。

地点

多专科儿童医院和独立手术中心。

患者/参与者:2013 年至 2017 年间,9 个不同外科专业的 65190 例小儿门诊手术。排除心胸服务和非疼痛手术的患者。

主要观察指标

从 2013 年到 2017 年,处方发生率、剂量、可用剂量数(即治疗持续时间)和最大体重基家庭阿片类药物可用量。其他独立变量包括性别、年龄、体重、种族/族裔、保险类型(私人与公共)和手术服务。

结果

2013 年至 2017 年,出院时开具阿片类药物出院带药处方的发生率为 18%至 21%,无明显趋势。然而,在开具阿片类药物的患者中,最大可用家庭剂量从 2013 年到 2017 年稳步下降(P<0.001)。这是由于开的剂量(即治疗持续时间)减少,以及从 2015 年开始,每个剂量的剂量减少。女性比男性更有可能接受阿片类药物治疗,公共保险的患者比私人保险的患者更有可能接受阿片类药物治疗。与白人患者相比,未披露种族和少数民族种族的患者以及少数民族患者更有可能接受阿片类药物治疗(均 P<0.0001)。

结论

从 2013 年到 2017 年,接受家庭阿片类药物处方和处方剂量的比例保持稳定,但治疗持续时间稳步下降,从 2015 年开始,每个剂量的剂量也减少。某些亚组患者更有可能开阿片类药物,需要进一步调查和确认。

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