Doğanay Melike, Cengaver Nagihan, Kızılkanat Kanşav Tunç, Öz Murat, Akbay Serap, Kokanali Mahmut Kuntay
Zekai Tahir Burak Woman's Health Education And Research Hospital, Ankara, Turkey.
J Exp Ther Oncol. 2019 Jan;13(1):55-58.
Large cell neuroendocrine carcinoma (LCNEC) of the ovary is a rare tumour. Its pure form without any associated surface epithelial stromal or germ cell component is more rarely seen. Its prognosis is generally very poor even when the diagnosis is made at an early stage. We report a case of pure large cell neuroendocrine tumour of ovary. The patient was a 73-year-old woman with symptom of pelvic pain. Ultrasonography detected an abdominal tumour larger than 10 cm. She underwent an exploratory laparotomy with resection of the pelvic mass. After the surgery six cycles of chemotherapy (Etoposide and Cisplatin) were administered to the woman. She is still healthy after the last chemotherapy. Due to the rarity of the disease, few number of reported cases and the lack of systematic population based studies or registry data, we reported this case.
卵巢大细胞神经内分泌癌（LCNEC）是一种罕见的肿瘤。其不伴有任何相关表面上皮间质或生殖细胞成分的纯形式更为少见。即使在早期诊断，其预后通常也非常差。我们报告一例卵巢纯大细胞神经内分泌肿瘤病例。患者为一名73岁女性，有盆腔疼痛症状。超声检查发现一个大于10厘米的腹部肿瘤。她接受了剖腹探查术并切除了盆腔肿块。术后对该女性进行了六个周期的化疗（依托泊苷和顺铂）。最后一次化疗后她仍然健康。由于该疾病罕见、报告病例数量少且缺乏基于系统人群的研究或登记数据，我们报告了此病例。
