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并非所有的皮质扩张都是相同的:哺乳动物新皮层和背侧丘脑的共同进化。

Not all cortical expansions are the same: the coevolution of the neocortex and the dorsal thalamus in mammals.

机构信息

Center for Neuroscience, University of California, Davis, CA, United States.

Center for Neuroscience, University of California, Davis, CA, United States; Department of Psychology, University of California, Davis, CA, United States.

出版信息

Curr Opin Neurobiol. 2019 Jun;56:78-86. doi: 10.1016/j.conb.2018.12.003. Epub 2019 Jan 15.

DOI:10.1016/j.conb.2018.12.003
PMID:30658218
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6551301/
Abstract

A central question in comparative neurobiology concerns how evolution has produced brains with expanded neocortices, composed of more areas with unique connectivity and functional properties. Some mammalian lineages, such as primates, exhibit exceptionally large cortices relative to the amount of sensory inputs from the dorsal thalamus, and this expansion is associated with a larger number of distinct cortical areas, composing a larger proportion of the cortical sheet. We propose a link between the organization of the neocortex and its expansion relative to the size of the dorsal thalamus, based on a combination of work in comparative neuroanatomy and experimental research.

摘要

比较神经生物学中的一个核心问题是,进化是如何产生具有扩展的新皮层的大脑的,这些大脑由具有独特连接和功能特性的更多区域组成。一些哺乳动物谱系,如灵长类动物,相对于来自背侧丘脑的感觉输入量,表现出异常大的皮质,这种扩展与更多不同的皮质区域相关联,构成了皮质板的更大比例。我们基于比较神经解剖学和实验研究的综合工作,提出了新皮层的组织与其相对于背侧丘脑大小的扩展之间的联系。

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