Scientific Marketing & Applications, Luminex Corporation, 12212 Technology Blvd, Austin, TX, 78727, United States.
Chemistry, Luminex Corporation, 12212 Technology Blvd, Austin, TX, 78727, United States.
Methods. 2019 Apr 1;158:2-11. doi: 10.1016/j.ymeth.2019.01.007. Epub 2019 Jan 17.
Multiplexed analysis has the advantage of allowing for simultaneous detection of multiple analytes in a single reaction vessel which reduces time, labor, and cost as compared to single-reaction-based detection methods. Microsphere-based suspension array technologies, such as the Luminex® xMAP® system, offer high-throughput detection of both protein and nucleic acid targets in multiple assay chemistries. After Luminex's founding in 1995, it quickly became the leader in bead-based multiplexing solutions. Today, xMAP Technology is the most widely adopted bead-based multiplexing platform with over 35,000 peer-reviewed publications, an installed base of approximately 15,500 instruments, and over 70 Luminex Partners offering more than 1300 research use kits as well as custom assay solutions. Because of the open architecture of the xMAP platform it has been implemented in a variety of applications that range from transplant medicine, biomarker discovery and validation, pathogen detection, drug discovery, vaccine development, personalized medicine, neurodegeneration, and cancer research.
多重分析的优势在于能够在单个反应容器中同时检测多种分析物，与基于单反应的检测方法相比，可减少时间、劳动力和成本。基于微球的悬浮阵列技术，如 Luminex® xMAP®系统，可在多种检测化学中高通量检测蛋白质和核酸靶标。Luminex 于 1995 年成立后，迅速成为基于珠粒的多重解决方案的领导者。如今，xMAP 技术是应用最广泛的基于珠粒的多重化平台，拥有超过 35,000 篇同行评审出版物，约 15,500 台仪器的安装基础，以及超过 70 家 Luminex 合作伙伴提供超过 1300 种研究用试剂盒和定制检测解决方案。由于 xMAP 平台的开放式架构，它已应用于各种应用中，包括移植医学、生物标志物的发现和验证、病原体检测、药物发现、疫苗开发、个性化医疗、神经退行性疾病和癌症研究。
