Reed E Kate, Steinmark Linda, Seibert Diane C, Edelman Emily
Semin Oncol Nurs. 2019 Feb;35(1):22-33. doi: 10.1016/j.soncn.2018.12.009. Epub 2019 Jan 17.
To provide an overview of key considerations for somatic testing for the purpose of targeting cancer treatment.
Literature; research reports.
Genomic testing of cancer cells to identify variants that drive the carcinogenic process is becoming common in clinical settings. Providers and patients need to weigh the potential benefits of testing with technologic and logistic issues.
Testing is available for thousands of genomic variants to identify one or more to guide targeted treatment. Oncology nurses need to understand the benefits and limitations of participating in patient-centered implementation of this testing.
概述为靶向癌症治疗进行体细胞检测的关键注意事项。
文献；研究报告。
对癌细胞进行基因组检测以识别驱动致癌过程的变异在临床环境中变得越来越普遍。医疗服务提供者和患者需要在检测的潜在益处与技术和后勤问题之间进行权衡。
针对数千种基因组变异都可进行检测，以识别一种或多种变异来指导靶向治疗。肿瘤学护士需要了解参与以患者为中心的此类检测实施的益处和局限性。
