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护士的精准医疗:基础入门

Precision medicine for nurses: 101.

作者信息

Lemoine Colleen

出版信息

Semin Oncol Nurs. 2014 May;30(2):84-99. doi: 10.1016/j.soncn.2014.03.002.

DOI:10.1016/j.soncn.2014.03.002
PMID:24794082
Abstract

OBJECTIVES

To introduce the key concepts and terms associated with precision medicine and support understanding of future developments in the field by providing an overview and history of precision medicine, related ethical considerations, and nursing implications.

DATA SOURCES

Current nursing, medical and basic science literature.

CONCLUSION

Rapid progress in understanding the oncogenic drivers associated with cancer is leading to a shift toward precision medicine, where treatment is based on targeting specific genetic and epigenetic alterations associated with a particular cancer.

IMPLICATIONS FOR NURSING PRACTICE

Nurses will need to embrace the paradigm shift to precision medicine, expend the effort necessary to learn the essential terminology, concepts and principles, and work collaboratively with physician colleagues to best position our patients to maximize the potential that precision medicine can offer.

摘要

目的

介绍与精准医学相关的关键概念和术语,通过概述精准医学的发展历程、相关伦理考量及护理启示,帮助理解该领域的未来发展。

数据来源

当前的护理、医学和基础科学文献。

结论

在了解与癌症相关的致癌驱动因素方面取得的快速进展正促使向精准医学转变,即治疗基于针对与特定癌症相关的特定基因和表观遗传改变。

对护理实践的启示

护士需要接受向精准医学的范式转变,付出必要努力学习基本术语、概念和原则,并与医生同事协作,以使我们的患者处于最佳位置,最大限度地发挥精准医学所能提供的潜力。

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