Salami Ayodeji A, Okunlola Abiodun I, Ajani Mustapha A, Adekanmbi Adefisayo A, Balogun James A
Department of Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Division of Neurosurgery, Department of Surgery, University College Hospital, Ibadan, Nigeria.
World Neurosurg. 2019 May;125:e94-e97. doi: 10.1016/j.wneu.2018.12.200. Epub 2019 Jan 17.
Meningiomas are the second commonest intracranial tumors in many places worldwide. They are rare in the pediatric age group, however, and most studies have been able to document only a few patients. Meningiomas in pediatric patients have also been shown to behave differently from those in the adult population. This study was done to examine histologic types of meningiomas seen in pediatric patients from a predominantly African population using the 2016 World Health Organization (WHO) grading system for intracranial tumors.
Data from the operating logs of patients and histology reports of the samples sent to the pathology department during the study period were extracted. The data obtained were the age, sex, location of the intracranial tumor, histologic diagnosis, WHO grade, and tumor recurrence.
Nine pediatric age patients were found among the 166 surgically excised meningiomas received at the pathology department in our institution over a 19-year period. The age range was from 8 months to 17 years. There was a male-to-female ratio of 1:2 with a female predominance. Six tumors were basally located. All tumors were WHO grade I with transitional meningiomas being the commonest followed by meningothelial. There was no history of recurrence in any of the tumors after complete surgical excisions.
Our study showed the rarity of meningiomas in the study population, and there was a predominance of basally located tumors.
脑膜瘤是全球许多地区第二常见的颅内肿瘤。然而，它们在儿童年龄组中较为罕见，大多数研究仅能记录少数患者。小儿患者的脑膜瘤也表现出与成人不同的行为。本研究旨在使用2016年世界卫生组织（WHO）颅内肿瘤分级系统，检查来自主要为非洲人群的小儿患者中所见脑膜瘤的组织学类型。
提取研究期间患者手术记录和送至病理科样本的组织学报告中的数据。获得的数据包括年龄、性别、颅内肿瘤位置、组织学诊断、WHO分级和肿瘤复发情况。
在我们机构病理科19年间接收的166例手术切除的脑膜瘤中，发现9例小儿患者。年龄范围为8个月至17岁。男女比例为1:2，女性占主导。6个肿瘤位于基底。所有肿瘤均为WHO I级，其中过渡型脑膜瘤最常见，其次是脑膜内皮型。所有肿瘤在完全手术切除后均无复发史。
我们的研究表明，研究人群中脑膜瘤罕见，且基底部位肿瘤占主导。
