Department of Chemistry, Gebze Technical University, 41400 Gebze, Kocaeli, Turkey.
Department of Chemical Engineering, Marmara University, 34722 Göztepe, Turkey.
Biosens Bioelectron. 2019 Mar 1;128:144-150. doi: 10.1016/j.bios.2018.12.052. Epub 2019 Jan 9.
In this work, 4,4-difluoro-8-(4-hydroxyphenyl)- 2,6-diethynly-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene (BODIPY) having double terminal ethynyl groups was synthesized. Three dimensional single walled carbon nanotube (SWCNT)-BODIPY hybrid material (3D SWCNT-BODIPY) was synthesized by the reaction of BODIPY bearing double terminal ethynyl groups with azido containing SWCNTs via "Click" reaction. The structural properties and electrochemical detection of eserine (a pesticide) on BODIPY functionalized SWCNTs as a three dimensional (3D) material were investigated. A glassy carbon electrode (GCE) was modified by 3D SWCNT-BODIPY hybrid material for the determination of eserine in the range of 0.25-2.25 μM. In the study by the square wave voltammetry (SWV), the bare GCE showed no response, while the new peak at - 0.6 V appeared in the case of the modified electrode. The detection limit and quantification were determined as 160 nM and 528 nM for eserine on the 3D SWCNT-BODIPY modified electrode, respectively. Eserine was also determined with a standard addition method in different brands of orange juices, and the recovery of eserine was obtained to be in the range of 102.09% and 103.22%. This study clearly indicates that the 3D SWCNT-BODIPY modified electrode tested as an electrochemical sensor was found to be highly selective and sensitive to eserine.
在这项工作中，合成了具有双末端炔基的 4,4-二氟-8-(4-羟基苯基)-2,6-二乙炔基-1,3,5,7-四甲基-4-硼-3a,4a-二氮杂-s-茚并[1,2-b]吡咯（BODIPY）。通过 BODIPY 上带有双末端炔基与叠氮化物官能化的单壁碳纳米管（SWCNT）之间的“点击”反应，合成了三维单壁碳纳米管（SWCNT）-BODIPY 杂化材料（3D SWCNT-BODIPY）。研究了作为三维（3D）材料的 BODIPY 功能化 SWCNTs 上的 eserine（一种农药）的结构性质和电化学检测。通过 3D SWCNT-BODIPY 杂化材料修饰玻碳电极（GCE），用于在 0.25-2.25 μM 范围内测定 eserine。在方波伏安法（SWV）研究中，裸 GCE 没有响应，而在修饰电极的情况下出现了新的-0.6 V 峰。在 3D SWCNT-BODIPY 修饰电极上，eserine 的检测限和定量限分别确定为 160 nM 和 528 nM。在不同品牌的橙汁中也使用标准加入法测定了 eserine，得到 eserine 的回收率在 102.09%和 103.22%之间。这项研究清楚地表明，作为电化学传感器测试的 3D SWCNT-BODIPY 修饰电极对 eserine 表现出高度的选择性和敏感性。
