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妇科住院患者不良事件的发生率、可预防性及死亡率:一项系统评价与荟萃分析

Incidence of adverse events, preventability and mortality in gynaecological hospital admissions: A systematic review and meta-analysis.

作者信息

Tanaka Keisuke, Eriksson Lars, Asher Rebecca, Obermair Andreas

机构信息

Women's and Newborn Services, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.

Faculty of Medicine, The University of Queensland, St Lucia, Queensland, Australia.

出版信息

Aust N Z J Obstet Gynaecol. 2019 Apr;59(2):195-200. doi: 10.1111/ajo.12937. Epub 2019 Jan 20.

Abstract

BACKGROUND

Adverse events (AEs) are unintended consequences of healthcare management that result in temporary or permanent disability, death or prolonged hospital stay. The incidence of AEs has been reported to be higher in surgical specialties compared to medical specialties but information on the incidence of AEs in gynaecology is sparse.

AIMS

To collect evidence on the incidence, preventability and mortality of AEs in gynaecological hospital admissions by conducting a systematic review and meta-analysis.

MATERIALS AND METHODS

A systematic search of the PubMed, EMBASE, and CINAHL electronic medical databases was performed. Identified articles were screened and a full-text review was conducted by two independent reviewers.

RESULTS

Of the 49 studies assessed for eligibility, three studies were included in this systematic review. Meta-analysis showed that the incidence of AEs in gynaecological hospital admissions was 10.8% (95% CI 9.4-12.1%), preventability was 52.5% (95% CI 47.3-57.7%) and mortality was 1.2% (95% CI 0-2.5%).

CONCLUSIONS

Evidence on AEs in gynaecological hospital admissions is limited. Available evidence suggests that approximately one in ten gynaecological inpatients suffer at least one AE and half of AEs are considered preventable. Further research is needed to determine strategies regarding how the incidence of preventable AEs can be reduced.

摘要

背景

不良事件(AE)是医疗管理中意外产生的后果,可导致暂时或永久性残疾、死亡或住院时间延长。据报道,与内科专业相比,外科专业中不良事件的发生率更高,但关于妇科不良事件发生率的信息却很少。

目的

通过进行系统评价和荟萃分析,收集有关妇科住院患者不良事件的发生率、可预防性和死亡率的证据。

材料与方法

对PubMed、EMBASE和CINAHL电子医学数据库进行系统检索。由两名独立的评审员对检索到的文章进行筛选并进行全文审查。

结果

在评估是否符合纳入标准的49项研究中,有3项研究被纳入本系统评价。荟萃分析表明,妇科住院患者不良事件的发生率为10.8%(95%可信区间9.4-12.1%),可预防性为52.5%(95%可信区间47.3-57.7%),死亡率为1.2%(95%可信区间0-2.5%)。

结论

关于妇科住院患者不良事件的证据有限。现有证据表明,大约每十名妇科住院患者中就有一人至少发生一次不良事件,且一半的不良事件被认为是可预防的。需要进一步研究以确定如何降低可预防不良事件发生率的策略。

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