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正常压力脑积水与痴呆——评估与治疗

Normal pressure hydrocephalus and dementia--evaluation and treatment.

作者信息

Turner D A, McGeachie R E

机构信息

Department of Neurosurgery, University of Minnesota, Minneapolis.

出版信息

Clin Geriatr Med. 1988 Nov;4(4):815-30.

PMID:3066462
Abstract

The evaluation of dementia usually includes a consideration of normal pressure hydrocephalus, which may be a treatable aspect of the patient's cognitive dysfunction. This article outlines clinical syndromes, standard radiologic evaluation, and newer diagnostic tests that may suggest cerebrospinal fluid (CSF) shunting. In general, patients who present with dementia alone will not respond well to CSF shunting because of cerebral atrophy and the lack of tension within the cerebral ventricles. However, normal pressure hydrocephalus remains a diagnostic consideration, and improved evaluation may allow a better differentiation of which patients should be considered for CSF shunting.

摘要

痴呆的评估通常包括对正常压力脑积水的考量,这可能是患者认知功能障碍中可治疗的一个方面。本文概述了临床综合征、标准影像学评估以及可能提示脑脊液分流的新型诊断测试。一般来说,仅表现为痴呆的患者对脑脊液分流的反应不佳,因为存在脑萎缩且脑室内缺乏张力。然而,正常压力脑积水仍是一个需要考虑的诊断因素,改进评估可能有助于更好地鉴别哪些患者应考虑进行脑脊液分流。

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