Lobo Antunes J, Fahn S, Cote L
J Neural Transm Suppl. 1983;19:225-31.
Three patients with normal pressure hydrocephalus and Parkinson's disease are reported. The recognition of this association is important because these two entities require specific therapeutic approaches. The presence of Parkinson's disease does not preclude an excellent response of the hydrocephalus to a shunting procedure. Although several reports of cases with the characteristic clinical manifestations of normal pressure hydrocephalus--progressive dementia, gait difficulty and urinary incontinence--have been published earlier, it was Adams and Hakim who emphasized the clinical triad and the effect of shunting the cerebrospinal fluid as a means of treatment. Messert and Baker stressed that the gait disturbance had a close resemblance to the freezing gait of parkinsonism. We are reporting three patients who had both conditions. Recognition of the existence of both disorders in the same patients is important since appropriate treatment of each of them led to marked improvement of their symptoms.
本文报告了3例患有正常压力脑积水和帕金森病的患者。认识到这两种疾病的关联很重要，因为这两种疾病需要特定的治疗方法。帕金森病的存在并不排除脑积水对分流手术有良好反应。尽管此前已经发表了几篇关于具有正常压力脑积水特征性临床表现（进行性痴呆、步态障碍和尿失禁）病例的报告，但正是亚当斯和哈基姆强调了这一临床三联征以及脑脊液分流作为一种治疗手段的效果。梅塞尔特和贝克强调，步态障碍与帕金森病的冻结步态非常相似。我们报告了3例同时患有这两种疾病的患者。认识到同一患者存在这两种疾病很重要，因为对每种疾病进行适当治疗都能显著改善他们的症状。
