Moss R J, Miles S H
University of Chicago, Illinois.
Clin Geriatr Med. 1988 Nov;4(4):889-95.
For the geriatrician who commonly evaluates cognitive and psychiatric disorders in the elderly, the neurologic consequences of infection with the human immunodeficiency virus (HIV) are of particular importance. The most frequent neurologic disease is the AIDS dementia complex characterized by cognitive, behavioral, and motor changes, occurring in two-thirds of AIDS patients. The pathophysiology of central nervous system HIV infection has been advanced with important implications for both the diagnosis and the potential treatment of this devastating disease.
对于经常评估老年人认知和精神疾病的老年病医生而言,感染人类免疫缺陷病毒(HIV)的神经学后果尤为重要。最常见的神经疾病是艾滋病痴呆综合征,其特征为认知、行为和运动改变,在三分之二的艾滋病患者中出现。中枢神经系统HIV感染的病理生理学已取得进展,对这种毁灭性疾病的诊断和潜在治疗都具有重要意义。