Suppr超能文献

腰椎管狭窄症患者脊柱减压对腰痛的影响:加拿大脊柱结局研究网络(CSORN)研究。

Effect of spinal decompression on back pain in lumbar spinal stenosis: a Canadian Spine Outcomes Research Network (CSORN) study.

机构信息

Vancouver Spine Surgery Institute, 10th Avenue West, Vancouver V5Z 1MZ, Canada.

CHA Hôpital Enfant-Jésus, Québec, Canada.

出版信息

Spine J. 2019 Jun;19(6):1001-1008. doi: 10.1016/j.spinee.2019.01.003. Epub 2019 Jan 19.

Abstract

BACKGROUND CONTEXT

Surgical decompression is usually offered for improvement of neurogenic claudication in patients with symptomatic lumbar canal stenosis. These patients often have associated low back pain (LBP) and little is known about the effect of decompression on this symptom.

PURPOSE

The goal of the present study is to specifically quantify the improvement in LBP following surgical decompression for lumbar canal stenosis and to identify factors associated with changes in LBP in this population.

STUDY DESIGN

This is a multicenter, retrospective review of consecutive spine surgery patients enrolled by the Canadian Spine Outcomes and Research Network.

PATIENT SAMPLE

Consecutive patients who underwent surgical treatment for symptomatic lumbar spine stenosis without instability between 2014 and 2017.

OUTCOME MEASURES

Change in LBP on the Numeric Rating Scale (NRS).

METHODS

Patient-reported outcomes were collected at baseline and at 3, 12, and 24 months after surgery. The primary outcome was change in LBP on the NRS. Multivariable logistic regression was used to model the relationship between the outcome and potential factors associated with achieving minimal clinical important difference in back pain using a backward selection procedure.

RESULTS

In all, 1,221 patients were included in the analysis. Mean age was 64 years and 58% were males. Baseline back pain scores were available in 1,133 patients and follow-up evaluations were available in 968/1,133 (85%) patients at 3 months, 649/903 (72%) patients at 12 months, and 331/454 (73%) at 24 months. LBP significantly improved 3 months after surgery and the improvement was sustained at 24 months (p<.001). We found that 74% of patients reached the minimal clinical important difference in back pain. Predictive factors for sustained improvement (12 and 24 months) in LBP after surgical intervention were absence of narcotic usage or compensation claims and increased severity of LBP before surgery (high NRS).

CONCLUSIONS

Alleviation of clinically significant LBP was observed at 3 months after lumbar decompression surgery for neurogenic claudication and was maintained at 12 and 24 months after surgery in the majority of patients.

摘要

背景

对于有症状的腰椎管狭窄症患者,手术减压通常用于改善神经性跛行。这些患者通常伴有下腰痛(LBP),但对于减压对该症状的影响知之甚少。

目的

本研究的目的是专门量化腰椎管狭窄症手术后 LBP 的改善情况,并确定与该人群 LBP 变化相关的因素。

研究设计

这是一项由加拿大脊柱结果和研究网络招募的多中心、回顾性脊柱手术患者研究。

患者样本

2014 年至 2017 年间接受手术治疗的有症状腰椎管狭窄症且无不稳定的连续脊柱手术患者。

观察指标

数字评分量表(NRS)上 LBP 的变化。

方法

患者报告的结果在基线时以及手术后 3、12 和 24 个月时收集。主要结果是 NRS 上 LBP 的变化。使用向后选择程序的多变量逻辑回归来模拟结果与与背部疼痛实现最小临床重要差异相关的潜在因素之间的关系。

结果

共纳入 1221 例患者进行分析。平均年龄为 64 岁,58%为男性。1133 例患者有基线腰痛评分,968/1133(85%)例患者在 3 个月时、649/903(72%)例患者在 12 个月时和 331/454(73%)例患者在 24 个月时进行了随访评估。手术后 3 个月时 LBP 明显改善,24 个月时仍持续改善(p<.001)。我们发现,74%的患者达到了背部疼痛的最小临床重要差异。手术干预后 LBP 持续改善(12 个月和 24 个月)的预测因素是无阿片类药物使用或赔偿要求以及术前 LBP 严重程度增加(高 NRS)。

结论

腰椎减压手术后 3 个月观察到神经性跛行的临床显著 LBP 缓解,大多数患者在手术后 12 个月和 24 个月时仍保持缓解。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验