Nielsen I K, Vinther S, Birch K, Lange A P
Department of Obstetrics and Gynaecology, Glostrup University Hospital, Denmark.
Diabetes Res. 1988 May;8(1):31-3.
Random blood glucose was measured on 1,992 pregnant women during the initial attendance at our antenatal clinic. The visit usually took place during the first part of the second trimester. Women with a random blood glucose concentration in excess of 6.1 mmol/l within 2 hours of the last meal and 5.6 mmol/l more than 2 hours after the last meal were referred for a fasting blood glucose measurement. A 75 g oral glucose tolerance test was performed in those cases where the fasting blood glucose exceeded 4.0 mmol/l. The cut-off levels were exceeded in 22 cases, but only one of these women was found to be suffering from previously unsuspected diabetes mellitus, based on the criteria of WHO (1). Five other cases of gestational diabetes were not detected by the random blood glucose method. It is concluded that random blood glucose measurements cannot be recommended as a safe and reliable screening procedure during the early part of the second trimester.
在我们产前诊所初次就诊时，对1992名孕妇进行了随机血糖测量。就诊通常在妊娠中期的前半段进行。最后一餐进食后2小时内随机血糖浓度超过6.1 mmol/L以及最后一餐进食2小时后超过5.6 mmol/L的孕妇被转诊进行空腹血糖测量。空腹血糖超过4.0 mmol/L的孕妇进行了75克口服葡萄糖耐量试验。有22例超过了临界值，但根据世界卫生组织（1）的标准，这些女性中只有1例被发现患有先前未被怀疑的糖尿病。另外5例妊娠期糖尿病未通过随机血糖法检测出来。结论是，在妊娠中期早期，随机血糖测量不能作为一种安全可靠的筛查方法被推荐。
