Sinnott J T, Gilchrist L S, Ellis L
Department of Internal Medicine, University of South Florida College of Medicine, Tampa.
Infect Control Hosp Epidemiol. 1988 Oct;9(10):465-8. doi: 10.1086/645745.
RSV is now understood to be the most significant viral respiratory pathogen of infants and is capable of causing both bronchiolitis and pneumonia. It is a particular risk to hospitalized infants as the virus is easily spread through close contact. The most vulnerable infants are those who suffer with either congenital heart disease or bronchopulmonary dysplasia who easily fall prey to pulmonary complications of infection. Strict environmental control and the use of protective clothing and eyewear should be implemented to decrease the nosocomial spread of RSV. Available diagnostic studies include viral isolation, fluorescent antibody stains, and enzyme immunoassays. Treatment of the disease is usually supportive but hospitalized patients frequently benefit from aerosolized ribavirin therapy. Hopefully, current vaccine trials will be successful and this pathogen will not only be treatable but will also be preventable.
呼吸道合胞病毒(RSV)现在被认为是婴儿最重要的病毒性呼吸道病原体,能够引起细支气管炎和肺炎。对于住院婴儿来说,它是一种特别的风险,因为该病毒很容易通过密切接触传播。最易感染的婴儿是患有先天性心脏病或支气管肺发育不良的婴儿,他们很容易受到感染引起的肺部并发症的影响。应实施严格的环境控制,并使用防护服和护目镜,以减少RSV的医院内传播。现有的诊断研究包括病毒分离、荧光抗体染色和酶免疫测定。该疾病的治疗通常是支持性的,但住院患者经常受益于雾化利巴韦林治疗。有望目前的疫苗试验能够成功,这样这种病原体不仅可以治疗,而且还可以预防。