Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Canada; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Canada; Krembil Research Institute, University Health Network, Toronto, Canada; Centre for Mental Health, University Health Network, Toronto, Canada; MRI-Guided rTMS Clinic, Poul Hansen Centre for Depression, University Health Network, Toronto, Canada.
Curr Biol. 2019 Jan 21;29(2):R59-R62. doi: 10.1016/j.cub.2018.11.057.
Self-perpetuating activity in lateral orbitofrontal regions has been theorized to sustain the negative thoughts and emotions of depression. A new study demonstrates that disrupting such activity may yield rapid improvements in mood state, pointing the way to novel treatment strategies.
据理论推测，外侧眶额区域的自我延续活动会维持抑郁的负面想法和情绪。一项新的研究表明，破坏这种活动可能会迅速改善情绪状态，为新的治疗策略指明方向。
